Reactome | PDS5B [chromosome, centromeric region]

PDS5B [chromosome, centromeric region]

Stable Identifier

R-SSC-2468263

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

chromosome, centromeric region

Synonyms

PDS5B, A0A286ZSB7

Locations in the PathwayBrowser

Expand all

Cell Cycle (Sus scrofa)

- Cell Cycle, Mitotic (Sus scrofa)
  - M Phase (Sus scrofa)
    - Mitotic Metaphase and Anaphase (Sus scrofa)
      - Mitotic Anaphase (Sus scrofa)
        
        Separation of Sister Chromatids (Sus scrofa)
        
        ESPL1 (Separase) cleaves centromeric cohesin (Sus scrofa)
        
        Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        PDS5 [chromosome, centromeric region] (Sus scrofa)
        
        PDS5B [chromosome, centromeric region] (Sus scrofa)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        PDS5 [chromosome, centromeric region] (Sus scrofa)
        
        PDS5B [chromosome, centromeric region] (Sus scrofa)
        
        Separation of sister chromatids (Sus scrofa)
        
        Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        PDS5 [chromosome, centromeric region] (Sus scrofa)
        
        PDS5B [chromosome, centromeric region] (Sus scrofa)
    - Mitotic Prometaphase (Sus scrofa)
      - Resolution of Sister Chromatid Cohesion (Sus scrofa)
        
        CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Sus scrofa)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Sus scrofa)
        
        PDS5 [chromosome, centromeric region] (Sus scrofa)
        
        PDS5B [chromosome, centromeric region] (Sus scrofa)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        PDS5 [chromosome, centromeric region] (Sus scrofa)
        
        PDS5B [chromosome, centromeric region] (Sus scrofa)
        
        Kinetochore assembly (Sus scrofa)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Sus scrofa)
        
        PDS5 [chromosome, centromeric region] (Sus scrofa)
        
        PDS5B [chromosome, centromeric region] (Sus scrofa)
        
        Sister Centromeres:Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Sus scrofa)
        
        Centromere:Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Sus scrofa)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Sus scrofa)
        
        PDS5 [chromosome, centromeric region] (Sus scrofa)
        
        PDS5B [chromosome, centromeric region] (Sus scrofa)
        
        PP2A-B56 dephosphorylates centromeric cohesin (Sus scrofa)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        PDS5 [chromosome, centromeric region] (Sus scrofa)
        
        PDS5B [chromosome, centromeric region] (Sus scrofa)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        PDS5 [chromosome, centromeric region] (Sus scrofa)
        
        PDS5B [chromosome, centromeric region] (Sus scrofa)
        
        Phosphorylation of cohesin by PLK1 at centromeres (Sus scrofa)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        PDS5 [chromosome, centromeric region] (Sus scrofa)
        
        PDS5B [chromosome, centromeric region] (Sus scrofa)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        PDS5 [chromosome, centromeric region] (Sus scrofa)
        
        PDS5B [chromosome, centromeric region] (Sus scrofa)
  - S Phase (Sus scrofa)
    - Establishment of Sister Chromatid Cohesion (Sus scrofa)
      - CDCA5 (Sororin) enables cohesion of sister centromeres (Sus scrofa)
        
        Sister Centromeres:Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Sus scrofa)
        
        Centromere:Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Sus scrofa)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Sus scrofa)
        
        PDS5 [chromosome, centromeric region] (Sus scrofa)
        
        PDS5B [chromosome, centromeric region] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A286ZSB7

Gene Names

PDS5B

Reference Genes

ENSEMBL:ENSSSCG00000009345.5

Other Identifiers

100154396

GO:0000278

GO:0000785

GO:0003677

GO:0005634

GO:0005654

GO:0005694

GO:0007059

GO:0007064

GO:0008285

GO:0042127

GO:0043226

GO:0140014

Ssc.21041.1.S1_at

Ssc.25238.1.S1_at

Ssc.8644.1.A1_at

Ssc.8644.2.A1_at

Participates

as a member of

PDS5 [chromosome, centromeric region] (Sus scrofa)

Other forms of this molecule

PDS5B [cytosol]

PDS5B [chromosome]

PDS5B [nucleoplasm]

Inferred From

PDS5B [chromosome, centromeric region] (Homo sapiens)

Cross References

OpenTargets

ENSG00000083642

Ensembl

ENSSSCT00000063159, ENSSSCG00000009345, ENSSSCP00000034360

VGNC

91290

Cite Us!