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DISC [plasma membrane]
Stable Identifier
R-SSC-2671814
Type
Set [DefinedSet]
Species
Sus scrofa
Compartment
cytosol
,
plasma membrane
Synonyms
death-inducing signaling complex
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Sus scrofa)
Apoptosis (Sus scrofa)
Caspase activation via extrinsic apoptotic signalling pathway (Sus scrofa)
Caspase activation via Death Receptors in the presence of ligand (Sus scrofa)
Regulation by c-FLIP (Sus scrofa)
Caspase-8 and FLIP(L) processing at DISC (Sus scrofa)
DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Sus scrofa)
DISC [plasma membrane] (Sus scrofa)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Sus scrofa)
DISC:procaspase-8 [plasma membrane] (Sus scrofa)
DISC [plasma membrane] (Sus scrofa)
Regulated Necrosis (Sus scrofa)
RIPK1-mediated regulated necrosis (Sus scrofa)
Regulation of necroptotic cell death (Sus scrofa)
CASP8 activity is inhibited (Sus scrofa)
FLIP(L) and procaspase-8 form heterodimer (Sus scrofa)
DISC:procaspase-8 [plasma membrane] (Sus scrofa)
DISC [plasma membrane] (Sus scrofa)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Sus scrofa)
DISC:procaspase-8 [plasma membrane] (Sus scrofa)
DISC [plasma membrane] (Sus scrofa)
FLIP(S) and procaspase-8 form heterodimer (Sus scrofa)
DISC:procaspase-8 [plasma membrane] (Sus scrofa)
DISC [plasma membrane] (Sus scrofa)
DISC:procaspase-8:FLIP(S) [plasma membrane] (Sus scrofa)
DISC:procaspase-8 [plasma membrane] (Sus scrofa)
DISC [plasma membrane] (Sus scrofa)
Participants
members
FASL:FAS Receptor Trimer:FADD [plasma membrane]
(Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol]
(Sus scrofa)
Participates
as a component of
DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Sus scrofa)
DISC:procaspase-8 [plasma membrane] (Sus scrofa)
Inferred From
DISC [plasma membrane]
(Homo sapiens)
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