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TP53 Tetramer [nucleoplasm]
Stable Identifier
R-SSC-3209194
Type
Complex
Species
Sus scrofa
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Sus scrofa)
Cell Cycle Checkpoints (Sus scrofa)
G1/S DNA Damage Checkpoints (Sus scrofa)
p53-Dependent G1/S DNA damage checkpoint (Sus scrofa)
p53-Dependent G1 DNA Damage Response (Sus scrofa)
Stabilization of p53 (Sus scrofa)
ATM phosphorylates TP53 at S15 (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
G2/M Checkpoints (Sus scrofa)
G2/M DNA damage checkpoint (Sus scrofa)
ATR phosphorylates TP53 (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular Senescence (Sus scrofa)
DNA Damage/Telomere Stress Induced Senescence (Sus scrofa)
ATM phosphorylates TP53 at S15 (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
Oxidative Stress Induced Senescence (Sus scrofa)
MAPKAPK5 phosphorylates TP53 (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
DNA Repair (Sus scrofa)
DNA Double-Strand Break Repair (Sus scrofa)
DNA Double Strand Break Response (Sus scrofa)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Sus scrofa)
ATM phosphorylates TP53 at S15 (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional Regulation by TP53 (Sus scrofa)
Regulation of TP53 Activity (Sus scrofa)
Regulation of TP53 Activity through Association with Co-factors (Sus scrofa)
BANP binds TP53 (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
TP53:BANP [nucleoplasm] (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
Regulation of TP53 Activity through Methylation (Sus scrofa)
EHMT1:EHMT2 dimethylates TP53 (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
Regulation of TP53 Activity through Phosphorylation (Sus scrofa)
AMPK phosphorylates TP53 (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
ATM phosphorylates TP53 at S15 (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
ATR phosphorylates TP53 (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
AURKA phosphorylates TP53 (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
CDK2 phosphorylates TP53 (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
CDK5 phosphorylates TP53 (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
MAPKAPK5 phosphorylates TP53 (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
NUAK1 phosphorylates TP53 (Sus scrofa)
TP53 Tetramer:STK11:p-T211-NUAK1 [nucleoplasm] (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
STK11 (LKB1) phosphorylates NUAK1 (Sus scrofa)
TP53 Tetramer:STK11:NUAK1 [nucleoplasm] (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
TP53 Tetramer:STK11:p-T211-NUAK1 [nucleoplasm] (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
TAF1 phosphorylates TP53 (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
TP53 binds HIPK1 (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
TP53 Tetramer:HIPK1 [nucleoplasm] (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
TP53 binds STK11 and NUAK1 (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
TP53 Tetramer:STK11:NUAK1 [nucleoplasm] (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
TP53RK phosphorylates TP53 (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
Regulation of TP53 Expression and Degradation (Sus scrofa)
Regulation of TP53 Degradation (Sus scrofa)
USP7 deubiquitinates TP53 and counteracts MDM2 (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
Regulation of TP53 Expression (Sus scrofa)
TP53 forms homotetramers (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
Transcriptional regulation by RUNX3 (Sus scrofa)
RUNX3 regulates CDKN1A transcription (Sus scrofa)
RUNX3 binds TP53 (Sus scrofa)
RUNX3:TP53 tetramer [nucleoplasm] (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
Immune System (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
Interferon Signaling (Sus scrofa)
Antiviral mechanism by IFN-stimulated genes (Sus scrofa)
PKR-mediated signaling (Sus scrofa)
p-PKR dimer phosphorylates TP53 tetramer (Sus scrofa)
TP53 Tetramer [nucleoplasm] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 4
TP53 [nucleoplasm]
(Sus scrofa)
Participates
as an input of
RUNX3 binds TP53 (Sus scrofa)
p-PKR dimer phosphorylates TP53 tetramer (Sus scrofa)
EHMT1:EHMT2 dimethylates TP53 (Sus scrofa)
BANP binds TP53 (Sus scrofa)
AURKA phosphorylates TP53 (Sus scrofa)
TP53 binds HIPK1 (Sus scrofa)
CDK2 phosphorylates TP53 (Sus scrofa)
CDK5 phosphorylates TP53 (Sus scrofa)
TP53 binds STK11 and NUAK1 (Sus scrofa)
TAF1 phosphorylates TP53 (Sus scrofa)
MAPKAPK5 phosphorylates TP53 (Sus scrofa)
AMPK phosphorylates TP53 (Sus scrofa)
TP53RK phosphorylates TP53 (Sus scrofa)
ATM phosphorylates TP53 at S15 (Sus scrofa)
ATR phosphorylates TP53 (Sus scrofa)
as a component of
RUNX3:TP53 tetramer [nucleoplasm] (Sus scrofa)
TP53:BANP [nucleoplasm] (Sus scrofa)
TP53 Tetramer:HIPK1 [nucleoplasm] (Sus scrofa)
TP53 Tetramer:STK11:p-T211-NUAK1 [nucleoplasm] (Sus scrofa)
TP53 Tetramer:STK11:NUAK1 [nucleoplasm] (Sus scrofa)
as an output of
USP7 deubiquitinates TP53 and counteracts MDM2 (Sus scrofa)
TP53 forms homotetramers (Sus scrofa)
Inferred From
TP53 Tetramer [nucleoplasm]
(Homo sapiens)
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