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DISC:procaspase-8 [plasma membrane]
Stable Identifier
R-SSC-3465443
Type
Complex
Species
Sus scrofa
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Sus scrofa)
Apoptosis (Sus scrofa)
Caspase activation via extrinsic apoptotic signalling pathway (Sus scrofa)
Caspase activation via Death Receptors in the presence of ligand (Sus scrofa)
Regulation by c-FLIP (Sus scrofa)
Caspase-8 and FLIP(L) processing at DISC (Sus scrofa)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Sus scrofa)
DISC:procaspase-8 [plasma membrane] (Sus scrofa)
Regulated Necrosis (Sus scrofa)
RIPK1-mediated regulated necrosis (Sus scrofa)
Regulation of necroptotic cell death (Sus scrofa)
CASP8 activity is inhibited (Sus scrofa)
FLIP(L) and procaspase-8 form heterodimer (Sus scrofa)
DISC:procaspase-8 [plasma membrane] (Sus scrofa)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Sus scrofa)
DISC:procaspase-8 [plasma membrane] (Sus scrofa)
FLIP(S) and procaspase-8 form heterodimer (Sus scrofa)
DISC:procaspase-8 [plasma membrane] (Sus scrofa)
DISC:procaspase-8:FLIP(S) [plasma membrane] (Sus scrofa)
DISC:procaspase-8 [plasma membrane] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
CASP8 [cytosol]
(Sus scrofa)
DISC [plasma membrane]
(Sus scrofa)
Participates
as an input of
FLIP(L) and procaspase-8 form heterodimer (Sus scrofa)
FLIP(S) and procaspase-8 form heterodimer (Sus scrofa)
as a component of
DISC:procaspase-8:FLIP(L) [plasma membrane] (Sus scrofa)
DISC:procaspase-8:FLIP(S) [plasma membrane] (Sus scrofa)
Inferred From
DISC:procaspase-8 [plasma membrane]
(Homo sapiens)
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