Reactome | OPRK1 [plasma membrane]

OPRK1 [plasma membrane]

Stable Identifier

R-SSC-374286

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

OPRK1, F1RSG5

Locations in the PathwayBrowser

Expand all

Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (i) signalling events (Sus scrofa)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        Opioid receptor:opioid ligand [plasma membrane] (Sus scrofa)
        
        Opioid receptors [plasma membrane] (Sus scrofa)
        
        OPRK1 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        Opioid receptor:opioid ligand [plasma membrane] (Sus scrofa)
        
        Opioid receptors [plasma membrane] (Sus scrofa)
        
        OPRK1 [plasma membrane] (Sus scrofa)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        Opioid receptor:opioid ligand [plasma membrane] (Sus scrofa)
        
        Opioid receptors [plasma membrane] (Sus scrofa)
        
        OPRK1 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        Opioid receptor:opioid ligand [plasma membrane] (Sus scrofa)
        
        Opioid receptors [plasma membrane] (Sus scrofa)
        
        OPRK1 [plasma membrane] (Sus scrofa)
      - The Ligand:GPCR:Gi complex dissociates (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        Opioid receptor:opioid ligand [plasma membrane] (Sus scrofa)
        
        Opioid receptors [plasma membrane] (Sus scrofa)
        
        OPRK1 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        Opioid receptor:opioid ligand [plasma membrane] (Sus scrofa)
        
        Opioid receptors [plasma membrane] (Sus scrofa)
        
        OPRK1 [plasma membrane] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
      - Peptide ligand-binding receptors (Sus scrofa)
        
        Opioid receptors bind opioid peptides (Sus scrofa)
        
        Opioid receptor:opioid ligand [plasma membrane] (Sus scrofa)
        
        Opioid receptors [plasma membrane] (Sus scrofa)
        
        OPRK1 [plasma membrane] (Sus scrofa)
        
        Opioid receptors [plasma membrane] (Sus scrofa)
        
        OPRK1 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RSG5

Gene Names

OPRK1

Reference Genes

BioGPS Gene:100152118 OPRK1

ENSEMBL:ENSSSCG00000006264.5

KEGG Gene (Sus scrofa):100152118 OPRK1

Monarch:100152118 OPRK1

NCBI Gene:100152118 OPRK1

Reference Transcript

RefSeq:XM_003355059.4 OPRK1

Other Identifiers

100152118

GO:0002376

GO:0004930

GO:0004985

GO:0005634

GO:0005654

GO:0005829

GO:0005886

GO:0006955

GO:0007165

GO:0007186

GO:0007218

GO:0016020

GO:0019233

GO:0023052

GO:0031635

GO:0038003

GO:0038048

GO:0042923

GO:0043005

GO:0043226

GO:0050877

GO:0051607

GO:0060089

GO:0098542

Ssc.16371.1.S1_at

Participates

as a member of

Opioid receptors [plasma membrane] (Sus scrofa)

Inferred From

OPRK1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_003355107.2

OpenTargets

ENSG00000082556

Ensembl

ENSSSCP00000006677, ENSSSCT00000006863, ENSSSCG00000006264

VGNC

91054