Reactome | PLK4 [cytosol]

PLK4 [cytosol]

Stable Identifier

R-SSC-380286

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

F1RRA8

Locations in the PathwayBrowser

Expand all

Organelle biogenesis and maintenance (Sus scrofa)

- Cilium Assembly (Sus scrofa)
  - Anchoring of the basal body to the plasma membrane (Sus scrofa)
    - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Sus scrofa)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        PLK4 [cytosol] (Sus scrofa)
      - mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        PLK4 [cytosol] (Sus scrofa)
    - C2CD3 binds the mother centriole (Sus scrofa)
      - mother centriole [cytosol] (Sus scrofa)
        
        PLK4 [cytosol] (Sus scrofa)
      - mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        PLK4 [cytosol] (Sus scrofa)
    - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Sus scrofa)
      - basal body:transition zone proteins [cytosol] (Sus scrofa)
        
        basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        PLK4 [cytosol] (Sus scrofa)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Sus scrofa)
        
        basal body:transition zone proteins [cytosol] (Sus scrofa)
        
        basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        PLK4 [cytosol] (Sus scrofa)
    - MARK4 binds ODF2 in the centriole (Sus scrofa)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Sus scrofa)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        PLK4 [cytosol] (Sus scrofa)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Sus scrofa)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Sus scrofa)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        PLK4 [cytosol] (Sus scrofa)
    - RAB3IP stimulates nucleotide exchange on RAB8A (Sus scrofa)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Sus scrofa)
        
        basal body:transition zone proteins [cytosol] (Sus scrofa)
        
        basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        PLK4 [cytosol] (Sus scrofa)
    - Recruitment of transition zone proteins (Sus scrofa)
      - basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        PLK4 [cytosol] (Sus scrofa)
      - basal body:transition zone proteins [cytosol] (Sus scrofa)
        
        basal body [cytosol] (Sus scrofa)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Sus scrofa)
        
        PLK4 [cytosol] (Sus scrofa)
    - The distal appendage proteins recruit TTBK2 (Sus scrofa)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        PLK4 [cytosol] (Sus scrofa)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Sus scrofa)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Sus scrofa)
        
        mother centriole:C2CD3 [cytosol] (Sus scrofa)
        
        mother centriole [cytosol] (Sus scrofa)
        
        PLK4 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RRA8

Reference Genes

ENSEMBL:ENSSSCG00000055606.1

Other Identifiers

100517044

GO:0000166

GO:0001741

GO:0003824

GO:0004672

GO:0004674

GO:0005515

GO:0005524

GO:0005634

GO:0005694

GO:0005730

GO:0005737

GO:0005813

GO:0005814

GO:0005815

GO:0005829

GO:0005856

GO:0005886

GO:0006468

GO:0007010

GO:0007099

GO:0016301

GO:0016310

GO:0016740

GO:0022414

GO:0030154

GO:0032154

GO:0036211

GO:0042802

GO:0043226

GO:0044782

GO:0046601

GO:0048856

GO:0060271

GO:0060707

GO:0098535

GO:0098536

GO:0120098

GO:0120099

GO:0140096

Ssc.25215.1.A1_at

Participates

as a component of

Inferred From

PLK4 [cytosol] (Homo sapiens)

Cross References

Ensembl

ENSSSCG00000055606, ENSSSCT00000009942, ENSSSCP00000009686

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