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Active PDGF dimers (AA, AB, BB) [extracellular region]
Stable Identifier
R-SSC-380760
Type
Set [DefinedSet]
Species
Sus scrofa
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Signal Transduction (Sus scrofa)
Intracellular signaling by second messengers (Sus scrofa)
PIP3 activates AKT signaling (Sus scrofa)
Negative regulation of the PI3K/AKT network (Sus scrofa)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Sus scrofa)
PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
Activator:PI3K [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
Activator:PI3K [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
MAPK family signaling cascades (Sus scrofa)
MAPK1/MAPK3 signaling (Sus scrofa)
RAF/MAP kinase cascade (Sus scrofa)
RAS GEFs promote RAS nucleotide exchange (Sus scrofa)
RAS GEFs [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by PDGF (Sus scrofa)
Autophosphorylation of PDGF alpha receptors (Sus scrofa)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PDGFR:type I PDGFR-binding TKIs [plasma membrane] (Sus scrofa)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
Phospho PDGF alpha receptor:PDGF dimers [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
Downstream signal transduction (Sus scrofa)
Activated PLC gamma dissociates from the PDGF receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
Activation of Src (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:MyrG-p-Y419-SRC [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
Crk binds to the active PDGF receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
GRB2:SOS1 complex binds to the active receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
Grb7 binds to the active PDGF receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:Grb7 [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
Nck binds to the active PDGF receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGFR receptor dimer:Nck [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PI3-kinase binds to the active receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PLC-gamma binds to the active receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
Phosphorylation of PLCgamma by PDGFR (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
SH2 domain of Src binds to the active receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
SHP2 binds to the active receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:SHP2 [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
STAT binds to the active receptor (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PDGF:phospho-PDGF receptor dimer:STAT [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
p130Cas and C3G bind PDGFR bound Crk (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PDGF dimer binds two receptors simultaneously (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PDGF:PDGF receptor dimer [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PDGFRs bind type I TKI (Sus scrofa)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
PDGFR:type I PDGFR-binding TKIs [plasma membrane] (Sus scrofa)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Sus scrofa)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
Participants
members
active PDGF-AA dimer [extracellular region]
(Sus scrofa)
active PDGF-BB dimer [extracellular region]
(Sus scrofa)
PDGF A/B heterodimer [extracellular region]
(Sus scrofa)
Participates
as a component of
PDGF:Phospho-PDGF receptor dimer:MyrG-p-Y419-SRC [plasma membrane] (Sus scrofa)
Phospho PDGF alpha receptor:PDGF dimers [plasma membrane] (Sus scrofa)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Sus scrofa)
PDGF:PDGF receptor dimer [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Sus scrofa)
as an input of
PDGF dimer binds two receptors simultaneously (Sus scrofa)
Inferred From
Active PDGF dimers (AA, AB, BB) [extracellular region]
(Homo sapiens)
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