Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phospho CD28:B7-1/B7-2 [plasma membrane]
Stable Identifier
R-SSC-388777
Type
Complex
Species
Sus scrofa
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Adaptive Immune System (Sus scrofa)
Costimulation by the CD28 family (Sus scrofa)
CD28 co-stimulation (Sus scrofa)
CD28 dependent PI3K/Akt signaling (Sus scrofa)
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
CD28:PI3K [plasma membrane] (Sus scrofa)
phospho CD28:B7-1/B7-2 [plasma membrane] (Sus scrofa)
PI3K binds CD28 (Sus scrofa)
CD28:PI3K [plasma membrane] (Sus scrofa)
phospho CD28:B7-1/B7-2 [plasma membrane] (Sus scrofa)
phospho CD28:B7-1/B7-2 [plasma membrane] (Sus scrofa)
CD28 dependent Vav1 pathway (Sus scrofa)
Activation of Cdc42 by pVav1 (Sus scrofa)
p-Y142,160,174-VAV1:PIP3:CD28:GRB2 [plasma membrane] (Sus scrofa)
CD28:Grb2 [plasma membrane] (Sus scrofa)
phospho CD28:B7-1/B7-2 [plasma membrane] (Sus scrofa)
Activation of Rac1 by pVav1 (Sus scrofa)
p-Y142,160,174-VAV1:PIP3:CD28:GRB2 [plasma membrane] (Sus scrofa)
CD28:Grb2 [plasma membrane] (Sus scrofa)
phospho CD28:B7-1/B7-2 [plasma membrane] (Sus scrofa)
Activation of Vav1 (Sus scrofa)
VAV1:PIP3:CD28:GRB2 [plasma membrane] (Sus scrofa)
CD28:Grb2 [plasma membrane] (Sus scrofa)
phospho CD28:B7-1/B7-2 [plasma membrane] (Sus scrofa)
p-Y142,160,174-VAV1:PIP3:CD28:GRB2 [plasma membrane] (Sus scrofa)
CD28:Grb2 [plasma membrane] (Sus scrofa)
phospho CD28:B7-1/B7-2 [plasma membrane] (Sus scrofa)
Grb2 binds CD28 (Sus scrofa)
CD28:Grb2 [plasma membrane] (Sus scrofa)
phospho CD28:B7-1/B7-2 [plasma membrane] (Sus scrofa)
phospho CD28:B7-1/B7-2 [plasma membrane] (Sus scrofa)
Translocation of Vav1 to CD28 (Sus scrofa)
CD28:Grb2 [plasma membrane] (Sus scrofa)
phospho CD28:B7-1/B7-2 [plasma membrane] (Sus scrofa)
VAV1:PIP3:CD28:GRB2 [plasma membrane] (Sus scrofa)
CD28:Grb2 [plasma membrane] (Sus scrofa)
phospho CD28:B7-1/B7-2 [plasma membrane] (Sus scrofa)
Gads binds CD28 (Sus scrofa)
CD28:GRAP2 [plasma membrane] (Sus scrofa)
phospho CD28:B7-1/B7-2 [plasma membrane] (Sus scrofa)
phospho CD28:B7-1/B7-2 [plasma membrane] (Sus scrofa)
Phosphorylation of CD28 (Sus scrofa)
phospho CD28:B7-1/B7-2 [plasma membrane] (Sus scrofa)
Signal Transduction (Sus scrofa)
Intracellular signaling by second messengers (Sus scrofa)
PIP3 activates AKT signaling (Sus scrofa)
Negative regulation of the PI3K/AKT network (Sus scrofa)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Sus scrofa)
PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
Activator:PI3K [plasma membrane] (Sus scrofa)
CD28:PI3K [plasma membrane] (Sus scrofa)
phospho CD28:B7-1/B7-2 [plasma membrane] (Sus scrofa)
PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
Activator:PI3K [plasma membrane] (Sus scrofa)
CD28:PI3K [plasma membrane] (Sus scrofa)
phospho CD28:B7-1/B7-2 [plasma membrane] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
B7-1 homodimer/ B7-2 [plasma membrane]
(Sus scrofa)
x 2
FYN,LCK [cytosol]
(Sus scrofa)
Phospho CD28 homodimer [plasma membrane]
(Sus scrofa)
Participates
as an input of
Gads binds CD28 (Sus scrofa)
Grb2 binds CD28 (Sus scrofa)
PI3K binds CD28 (Sus scrofa)
as a component of
CD28:GRAP2 [plasma membrane] (Sus scrofa)
CD28:Grb2 [plasma membrane] (Sus scrofa)
CD28:PI3K [plasma membrane] (Sus scrofa)
as an output of
Phosphorylation of CD28 (Sus scrofa)
Inferred From
phospho CD28:B7-1/B7-2 [plasma membrane]
(Homo sapiens)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text