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PHC2 [nucleoplasm]
Stable Identifier
R-SSC-389112
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
nucleoplasm
Synonyms
PHC2, I3LIR0
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular Senescence (Sus scrofa)
Oxidative Stress Induced Senescence (Sus scrofa)
PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter (Sus scrofa)
CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm] (Sus scrofa)
PRC1.4 [nucleoplasm] (Sus scrofa)
PHC1,PHC2,PHC3 [nucleoplasm] (Sus scrofa)
PHC2 [nucleoplasm] (Sus scrofa)
PRC1.4 [nucleoplasm] (Sus scrofa)
PHC1,PHC2,PHC3 [nucleoplasm] (Sus scrofa)
PHC2 [nucleoplasm] (Sus scrofa)
p-MAPKAPK3 phosphorylates BMI1 (Sus scrofa)
CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm] (Sus scrofa)
PRC1.4 [nucleoplasm] (Sus scrofa)
PHC1,PHC2,PHC3 [nucleoplasm] (Sus scrofa)
PHC2 [nucleoplasm] (Sus scrofa)
p-PRC1.4 complex [nucleoplasm] (Sus scrofa)
PHC1,PHC2,PHC3 [nucleoplasm] (Sus scrofa)
PHC2 [nucleoplasm] (Sus scrofa)
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional regulation by RUNX1 (Sus scrofa)
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known (Sus scrofa)
RUNX1 binds PRC1 complexes (Sus scrofa)
(PRC1.4,PRC1.5) [nucleoplasm] (Sus scrofa)
PRC1.4 [nucleoplasm] (Sus scrofa)
PHC1,PHC2,PHC3 [nucleoplasm] (Sus scrofa)
PHC2 [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:(PRC1.4,PRC1.5) [nucleoplasm] (Sus scrofa)
(PRC1.4,PRC1.5) [nucleoplasm] (Sus scrofa)
PRC1.4 [nucleoplasm] (Sus scrofa)
PHC1,PHC2,PHC3 [nucleoplasm] (Sus scrofa)
PHC2 [nucleoplasm] (Sus scrofa)
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
SUMOylation (Sus scrofa)
SUMO E3 ligases SUMOylate target proteins (Sus scrofa)
SUMOylation of DNA damage response and repair proteins (Sus scrofa)
CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 (Sus scrofa)
PRC1 complex [nucleoplasm] (Sus scrofa)
PHC1,PHC2,PHC3 [nucleoplasm] (Sus scrofa)
PHC2 [nucleoplasm] (Sus scrofa)
SUMOylation of RNA binding proteins (Sus scrofa)
CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 (Sus scrofa)
PRC1 complex [nucleoplasm] (Sus scrofa)
PHC1,PHC2,PHC3 [nucleoplasm] (Sus scrofa)
PHC2 [nucleoplasm] (Sus scrofa)
SUMOylation of chromatin organization proteins (Sus scrofa)
CBX4 SUMOylates BMI1 in PRC1 with SUMO1 (Sus scrofa)
PRC1 complex [nucleoplasm] (Sus scrofa)
PHC1,PHC2,PHC3 [nucleoplasm] (Sus scrofa)
PHC2 [nucleoplasm] (Sus scrofa)
monoSUMO1-BMI1:PRC1 [nucleoplasm] (Sus scrofa)
PHC2 [nucleoplasm] (Sus scrofa)
CBX4 SUMOylates CBX4 in PRC1 with SUMO1 (Sus scrofa)
PRC1 complex [nucleoplasm] (Sus scrofa)
PHC1,PHC2,PHC3 [nucleoplasm] (Sus scrofa)
PHC2 [nucleoplasm] (Sus scrofa)
monoSUMO1-CBX4:PRC1 [nucleoplasm] (Sus scrofa)
PHC2 [nucleoplasm] (Sus scrofa)
SUMOylation of transcription cofactors (Sus scrofa)
PRC1 SUMOylates CASP8AP2 with SUMO1 (Sus scrofa)
PRC1 complex [nucleoplasm] (Sus scrofa)
PHC1,PHC2,PHC3 [nucleoplasm] (Sus scrofa)
PHC2 [nucleoplasm] (Sus scrofa)
PRC1 SUMOylates CTBP1 with SUMO1 (Sus scrofa)
PRC1 complex [nucleoplasm] (Sus scrofa)
PHC1,PHC2,PHC3 [nucleoplasm] (Sus scrofa)
PHC2 [nucleoplasm] (Sus scrofa)
PRC1 SUMOylates CTBP1 with SUMO2,3 (Sus scrofa)
PRC1 complex [nucleoplasm] (Sus scrofa)
PHC1,PHC2,PHC3 [nucleoplasm] (Sus scrofa)
PHC2 [nucleoplasm] (Sus scrofa)
Signal Transduction (Sus scrofa)
Intracellular signaling by second messengers (Sus scrofa)
PIP3 activates AKT signaling (Sus scrofa)
PTEN Regulation (Sus scrofa)
Regulation of PTEN gene transcription (Sus scrofa)
MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter (Sus scrofa)
MECOM:(PRC1.4,PRC2 (EZH2) core):PTEN gene [nucleoplasm] (Sus scrofa)
MECOM:(PRC1.4,PRC2 (EZH2) core) [nucleoplasm] (Sus scrofa)
PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Sus scrofa)
PRC1.4 [nucleoplasm] (Sus scrofa)
PHC1,PHC2,PHC3 [nucleoplasm] (Sus scrofa)
PHC2 [nucleoplasm] (Sus scrofa)
PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Sus scrofa)
PRC1.4 [nucleoplasm] (Sus scrofa)
PHC1,PHC2,PHC3 [nucleoplasm] (Sus scrofa)
PHC2 [nucleoplasm] (Sus scrofa)
External Reference Information
External Reference
UniProt:I3LIR0
Gene Names
PHC2
Reference Genes
ENSEMBL:ENSSSCG00000025344.4
Other Identifiers
100622975
GO:0000792
GO:0003677
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0007283
GO:0008270
GO:0022414
GO:0031519
GO:0032991
GO:0035102
GO:0042802
GO:0043226
GO:0046872
Ssc.1845.1.S1_at
Participates
as a component of
monoSUMO1-CBX4:PRC1 [nucleoplasm] (Sus scrofa)
monoSUMO1-BMI1:PRC1 [nucleoplasm] (Sus scrofa)
as a member of
PHC1,PHC2,PHC3 [nucleoplasm] (Sus scrofa)
Inferred From
PHC2 [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000134686
Ensembl
ENSSSCT00000024539
,
ENSSSCG00000025344
,
ENSSSCP00000023966
VGNC
91371
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