Reactome | TNNI3 [cytosol]

TNNI3 [cytosol]

Stable Identifier

R-SSC-390542

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

A0A5G2QJI6

Locations in the PathwayBrowser

Expand all

Muscle contraction (Sus scrofa)

- Cardiac conduction (Sus scrofa)
  - Ion homeostasis (Sus scrofa)
    - PRKACA phosphorylates TNNI3 (Sus scrofa)
      - TNNI3 [cytosol] (Sus scrofa)
- Striated Muscle Contraction (Sus scrofa)
  - ATP Hydrolysis By Myosin (Sus scrofa)
    - ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Sus scrofa)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Sus scrofa)
        
        Calcium:Troponin Complex [cytosol] (Sus scrofa)
        
        Troponin I [cytosol] (Sus scrofa)
        
        TNNI3 [cytosol] (Sus scrofa)
    - ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Sus scrofa)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Sus scrofa)
        
        Calcium:Troponin Complex [cytosol] (Sus scrofa)
        
        Troponin I [cytosol] (Sus scrofa)
        
        TNNI3 [cytosol] (Sus scrofa)
  - Calcium Binds Troponin-C (Sus scrofa)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Sus scrofa)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Sus scrofa)
        
        Calcium:Troponin Complex [cytosol] (Sus scrofa)
        
        Troponin I [cytosol] (Sus scrofa)
        
        TNNI3 [cytosol] (Sus scrofa)
    - Inactive Sarcomere Protein Complex [cytosol] (Sus scrofa)
      - Thin Filament [cytosol] (Sus scrofa)
        
        Troponin Complex [cytosol] (Sus scrofa)
        
        Troponin I [cytosol] (Sus scrofa)
        
        TNNI3 [cytosol] (Sus scrofa)
  - Myosin Binds ATP (Sus scrofa)
    - ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Sus scrofa)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Sus scrofa)
        
        Calcium:Troponin Complex [cytosol] (Sus scrofa)
        
        Troponin I [cytosol] (Sus scrofa)
        
        TNNI3 [cytosol] (Sus scrofa)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Sus scrofa)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Sus scrofa)
        
        Calcium:Troponin Complex [cytosol] (Sus scrofa)
        
        Troponin I [cytosol] (Sus scrofa)
        
        TNNI3 [cytosol] (Sus scrofa)
  - Release Of ADP From Myosin (Sus scrofa)
    - ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Sus scrofa)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Sus scrofa)
        
        Calcium:Troponin Complex [cytosol] (Sus scrofa)
        
        Troponin I [cytosol] (Sus scrofa)
        
        TNNI3 [cytosol] (Sus scrofa)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Sus scrofa)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Sus scrofa)
        
        Calcium:Troponin Complex [cytosol] (Sus scrofa)
        
        Troponin I [cytosol] (Sus scrofa)
        
        TNNI3 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A5G2QJI6

Reference Genes

ENSEMBL:ENSSSCG00000043687.2

ENSEMBL:ENSSSCG00005008234.1

Other Identifiers

100049696

GO:0001570

GO:0001980

GO:0003012

GO:0003013

GO:0003779

GO:0005856

GO:0005861

GO:0006874

GO:0006937

GO:0006941

GO:0007507

GO:0008092

GO:0010882

GO:0019855

GO:0019901

GO:0019904

GO:0023052

GO:0030017

GO:0030154

GO:0030172

GO:0031014

GO:0043226

GO:0048306

GO:0048856

GO:0050877

GO:0051015

GO:0055010

GO:0055065

GO:0060047

GO:0060048

GO:0097512

GO:0098772

GO:1990584

Ssc.2589.1.S1_at

Participates

as a member of

Troponin I [cytosol] (Sus scrofa)

as an input of

PRKACA phosphorylates TNNI3 (Sus scrofa)

Other forms of this molecule

phospho-p-S23,S24-TNNI3 [cytosol]

Inferred From

TNNI3 [cytosol] (Homo sapiens)

Cross References

Ensembl

ENSSSCT00000091042, ENSSSCG00000043687, ENSSSCP00000064102