Reactome | SFTPD oligomer [extracellular region]

SFTPD oligomer [extracellular region]

Stable Identifier

R-SSC-391097

Type

Polymer

Species

Sus scrofa

Compartment

extracellular region

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

repeated unit

SFTPD trimer [extracellular region] (Sus scrofa)

Participates

as a member of

Collagen types I,II,III/SP-D [extracellular region] (Sus scrofa)

as an input of

SIRPA binds SFTPA oligomer, SFTPD oligomer (Sus scrofa)
SFTPA/SFTPD binds TLR4:LY96 (Sus scrofa)
SFTPA/SFTPD binds TLR2:TLR1 (Sus scrofa)

as a component of

SIRPA:SFTPA oligomer, SFTPD oligomer [plasma membrane] (Sus scrofa)
SP-A/SP-D:TLR4:MD2 [plasma membrane] (Sus scrofa)
SFTPA/SFTPD:TLR2:TLR1 [plasma membrane] (Sus scrofa)

This entity regulates

Negatively

Transfer of LPS onto TLR4 (Sus scrofa)

Inferred From

SFTPA oligomer, SFTPD oligomer [extracellular region] (Homo sapiens)

SFTPD oligomer [extracellular region] (Homo sapiens)

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