Reactome | NPM1 [nucleoplasm]

NPM1 [nucleoplasm]

Stable Identifier

R-SSC-4086039

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

monoSUMO1-K263-NPM1, I3LUP6

Locations in the PathwayBrowser

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Metabolism of proteins (Sus scrofa)

- Post-translational protein modification (Sus scrofa)
  - SUMOylation (Sus scrofa)
    - SUMO E3 ligases SUMOylate target proteins (Sus scrofa)
      - SUMOylation of transcription cofactors (Sus scrofa)
        
        SUMOylation of NPM1 with SUMO1 (Sus scrofa)
        
        NPM1 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:I3LUP6

Gene Names

NPM1

Reference Genes

BioGPS Gene:100525313 NPM1

ENSEMBL:ENSSSCG00000016998.5

KEGG Gene (Sus scrofa):100525313 NPM1

Monarch:100525313 NPM1

NCBI Gene:100525313 NPM1

Reference Transcript

RefSeq:XM_013990662.1 NPM1

Other Identifiers

100525313

GO:0000055

GO:0000056

GO:0001046

GO:0001558

GO:0001652

GO:0003677

GO:0003713

GO:0003723

GO:0004860

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005813

GO:0005815

GO:0005829

GO:0005840

GO:0005856

GO:0006281

GO:0006325

GO:0006334

GO:0006351

GO:0006355

GO:0006407

GO:0006884

GO:0006913

GO:0007010

GO:0007098

GO:0008104

GO:0008284

GO:0008285

GO:0010608

GO:0010629

GO:0010824

GO:0010825

GO:0010826

GO:0012501

GO:0015934

GO:0015935

GO:0016071

GO:0016607

GO:0019843

GO:0019901

GO:0023052

GO:0030957

GO:0031328

GO:0031398

GO:0031616

GO:0031647

GO:0032991

GO:0032993

GO:0034644

GO:0036211

GO:0042254

GO:0042273

GO:0042274

GO:0042393

GO:0042802

GO:0042803

GO:0043023

GO:0043024

GO:0043066

GO:0043226

GO:0043516

GO:0045727

GO:0045893

GO:0045944

GO:0046599

GO:0048025

GO:0050821

GO:0051059

GO:0051082

GO:0051726

GO:0060090

GO:0060735

GO:0065003

GO:0090398

GO:0098772

GO:0140110

GO:0140297

GO:0140693

GO:1902629

GO:1902751

GO:1904751

GO:1990904

Ssc.16541.1.S1_at

Participates

as an output of

SUMOylation of NPM1 with SUMO1 (Sus scrofa)

Other forms of this molecule

NPM1 [nucleoplasm]

phospho-NPM1 [cytosol]

NPM1 [cytosol]

Inferred From

monoSUMO1-K263-NPM1 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 263 (in Homo sapiens)

Coordinate

263

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Cross References

RefSeq

XP_013846116.1

OpenTargets

ENSG00000181163

Ensembl

ENSSSCT00000028813, ENSSSCP00000027846, ENSSSCG00000016998

VGNC

104010

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