Reactome | H3C14 [nucleoplasm]

H3C14 [nucleoplasm]

Stable Identifier

R-SSC-427744

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

Me3K10-HIST2H3A, A0A286ZJQ0

Locations in the PathwayBrowser

Expand all

Signal Transduction (Sus scrofa)

- Signaling by Nuclear Receptors (Sus scrofa)
  - ESR-mediated signaling (Sus scrofa)
    - Estrogen-dependent gene expression (Sus scrofa)
      - ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers (Sus scrofa)
        
        KDM4B-regulated genes:H3K9me3 nucleosome [nucleoplasm] (Sus scrofa)
        
        Nucleosome with H3K9me3 [nucleoplasm] (Sus scrofa)
        
        H3K9me3 [nucleoplasm] (Sus scrofa)
        
        H3C14 [nucleoplasm] (Sus scrofa)
        
        KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm] (Sus scrofa)
        
        KDM4B-regulated genes:H3K9me3 nucleosome [nucleoplasm] (Sus scrofa)
        
        Nucleosome with H3K9me3 [nucleoplasm] (Sus scrofa)
        
        H3K9me3 [nucleoplasm] (Sus scrofa)
        
        H3C14 [nucleoplasm] (Sus scrofa)
      - KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers (Sus scrofa)
        
        KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm] (Sus scrofa)
        
        KDM4B-regulated genes:H3K9me3 nucleosome [nucleoplasm] (Sus scrofa)
        
        Nucleosome with H3K9me3 [nucleoplasm] (Sus scrofa)
        
        H3K9me3 [nucleoplasm] (Sus scrofa)
        
        H3C14 [nucleoplasm] (Sus scrofa)
- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Sus scrofa)
  - Signaling by Rho GTPases (Sus scrofa)
    - RHO GTPase Effectors (Sus scrofa)
      - RHO GTPases activate PKNs (Sus scrofa)
        
        Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Sus scrofa)
        
        PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters (Sus scrofa)
        
        p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Sus scrofa)
        
        KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Sus scrofa)
        
        Nucleosome with H3K9me3 [nucleoplasm] (Sus scrofa)
        
        H3K9me3 [nucleoplasm] (Sus scrofa)
        
        H3C14 [nucleoplasm] (Sus scrofa)
        
        PKN1:AR complex binds promoters of KLK2 and KLK3 genes (Sus scrofa)
        
        KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Sus scrofa)
        
        Nucleosome with H3K9me3 [nucleoplasm] (Sus scrofa)
        
        H3K9me3 [nucleoplasm] (Sus scrofa)
        
        H3C14 [nucleoplasm] (Sus scrofa)
        
        p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Sus scrofa)
        
        KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Sus scrofa)
        
        Nucleosome with H3K9me3 [nucleoplasm] (Sus scrofa)
        
        H3K9me3 [nucleoplasm] (Sus scrofa)
        
        H3C14 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A286ZJQ0

Gene Names

H3C14

Reference Genes

BioGPS Gene:100156741 H3C14

ENSEMBL:ENSSSCG00000063270.1

KEGG:ssc:100156741 H3C14

Monarch:100156741 H3C14

NCBI Gene:100156741 H3C14

UCSC:A0A286ZJQ0 H3C14

Reference Transcript

Other Identifiers

100156741

102161782

GO:0000786

GO:0003677

GO:0005198

GO:0005634

GO:0005694

GO:0030527

GO:0043226

GO:0046982

Ssc.24432.1.S1_at

Participates

as a candidate of

Me3K10-histone H3 [nucleoplasm] (Sus scrofa)

as a member of

H3K9me3 [nucleoplasm] (Sus scrofa)

Other forms of this molecule

H3C14 [nucleoplasm]

phospho-H3C14 [nucleoplasm]

H3C14 [nucleoplasm]

H3C14 [cytosol]

H3C14 [nucleoplasm]

phospho-H3C14 [nucleoplasm]

H3C14 [nucleoplasm]

Inferred From

Me3K10-HIST2H3A [nucleoplasm] (Homo sapiens)

Modified Residues

Name

N6,N6,N6-trimethyl-L-lysine at 10 (in Homo sapiens)

Coordinate

PsiMod Name

N6,N6,N6-trimethyl-L-lysine [MOD:00083]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6,N6,N6-trimethyl-L-lysine.

Cross References

RefSeq

XP_013852656.1, NP_001231571.1

ENSEMBL

ENSSSCG00000063270, ENSSSCP00000080813, ENSSSCT00000098543, ENSSSCP00000074945, ENSSSCG00000053902, ENSSSCT00000092571