Reactome | PROK2 [extracellular region]

PROK2 [extracellular region]

Stable Identifier

R-SSC-444660

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

extracellular region

Synonyms

PROK2, I3LHX2

Locations in the PathwayBrowser

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Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (q) signalling events (Sus scrofa)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Sus scrofa)
        
        PROK1,PROK2 [extracellular region] (Sus scrofa)
        
        PROK2 [extracellular region] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Sus scrofa)
        
        PROK1,PROK2 [extracellular region] (Sus scrofa)
        
        PROK2 [extracellular region] (Sus scrofa)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Sus scrofa)
        
        PROK1,PROK2 [extracellular region] (Sus scrofa)
        
        PROK2 [extracellular region] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Sus scrofa)
        
        PROK1,PROK2 [extracellular region] (Sus scrofa)
        
        PROK2 [extracellular region] (Sus scrofa)
      - The Ligand:GPCR:Gq complex dissociates (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Sus scrofa)
        
        PROK1,PROK2 [extracellular region] (Sus scrofa)
        
        PROK2 [extracellular region] (Sus scrofa)
        
        Ligands of GPCRs that activate Gq/11 [extracellular region] (Sus scrofa)
        
        PROK1,PROK2 [extracellular region] (Sus scrofa)
        
        PROK2 [extracellular region] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
      - Peptide ligand-binding receptors (Sus scrofa)
        
        Prokineticin receptors bind prokineticin (Sus scrofa)
        
        PROK1,PROK2 [extracellular region] (Sus scrofa)
        
        PROK2 [extracellular region] (Sus scrofa)
        
        PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Sus scrofa)
        
        PROK1,PROK2 [extracellular region] (Sus scrofa)
        
        PROK2 [extracellular region] (Sus scrofa)

External Reference Information

External Reference

UniProt:I3LHX2

Gene Names

PROK2

Reference Genes

ENSEMBL:ENSSSCG00000026200.4

UCSC:I3LHX2 PROK2

Other Identifiers

100526076

GO:0001525

GO:0001935

GO:0003012

GO:0005576

GO:0006935

GO:0007283

GO:0007623

GO:0012501

GO:0022414

GO:0043066

GO:0045987

GO:0048856

Participates

as a member of

PROK1,PROK2 [extracellular region] (Sus scrofa)

Inferred From

PROK2 [extracellular region] (Homo sapiens)

Cross References

ENSEMBL

ENSSSCT00000022311, ENSSSCP00000023671, ENSSSCG00000026200

VGNC

91831