Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol]
Stable Identifier
R-SSC-446682
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
F1RZU1
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
Signaling by Interleukins (Sus scrofa)
Interleukin-1 family signaling (Sus scrofa)
Interleukin-1 signaling (Sus scrofa)
Hyperphosphorylated IRAK1 associates with TRAF6 (Sus scrofa)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1 [plasma membrane] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1:TRAF6 [plasma membrane] (Sus scrofa)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1 [plasma membrane] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
IRAK1 induces oligomerisation of TRAF6 (Sus scrofa)
hp-IRAK1:3xTRAF6 [cytosol] (Sus scrofa)
p-2S,S376,T,T209,T387-IRAK1:TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
p-2S,S376,T,T209,T387-IRAK1:TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
IRAK4-activated IRAK1 autophosphorylates (Sus scrofa)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1 [plasma membrane] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
Pellino ubiquitinates IRAK1 (Sus scrofa)
hp-IRAK1: p-Pellino-1,2,(3):UBE2N:UBE2V1:K63polyUb [cytosol] (Sus scrofa)
hp-IRAK1: p-Pellino-1,2,(3) [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
Polyubiquitinated TRAF6 binds the TAK1 complex (Sus scrofa)
hp-IRAK1:3xK63polyUb-TRAF6 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63polyUb-TRAF6 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
TAK1 is activated within the TAK1 complex (Sus scrofa)
hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63polyUb-TRAF6 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
TRAF6 binding leads to IRAK1:TRAF6 release (Sus scrofa)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1:TRAF6 [plasma membrane] (Sus scrofa)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1 [plasma membrane] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
p-2S,S376,T,T209,T387-IRAK1:TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
TRAF6 is K63 poly-ubiquitinated (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
hp-IRAK1:3xTRAF6:3xUBE2N:UBE2V1:K63polyUb [cytosol] (Sus scrofa)
hp-IRAK1:3xTRAF6 [cytosol] (Sus scrofa)
p-2S,S376,T,T209,T387-IRAK1:TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
UBE2N:UBE2V1 dissociates from hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
hp-IRAK1:3xK63polyUb-TRAF6 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2 (Sus scrofa)
hp-IRAK1:Pellino, IRAK4:Pellino [cytosol] (Sus scrofa)
hp-IRAK1: Pellino-1,2,3 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
hp-IRAK1:p-Pellino, IRAK4:p-Pellino [cytosol] (Sus scrofa)
hp-IRAK1: p-Pellino-1,2,(3) [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
hp-IRAK1,hp-IRAK4 bind Pellino1,2,3 (Sus scrofa)
hp-IRAK1:Pellino, IRAK4:Pellino [cytosol] (Sus scrofa)
hp-IRAK1: Pellino-1,2,3 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
p-2S,S376,T,T209,T387-IRAK1, IRAK4 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
hp-IRAK1:3xTRAF6 binds UBE2N:UBE2V1:K63-polyUb (Sus scrofa)
hp-IRAK1:3xTRAF6 [cytosol] (Sus scrofa)
p-2S,S376,T,T209,T387-IRAK1:TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
hp-IRAK1:3xTRAF6:3xUBE2N:UBE2V1:K63polyUb [cytosol] (Sus scrofa)
hp-IRAK1:3xTRAF6 [cytosol] (Sus scrofa)
p-2S,S376,T,T209,T387-IRAK1:TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
hp-IRAK1:p-Pellino, IRAK4:p-Pellino bind UBE2N:UBE2V1 (Sus scrofa)
IRAK1:Pellino:E2 complexes [cytosol] (Sus scrofa)
hp-IRAK1: p-Pellino-1,2,(3):UBE2N:UBE2V1:K63polyUb [cytosol] (Sus scrofa)
hp-IRAK1: p-Pellino-1,2,(3) [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
hp-IRAK1:p-Pellino, IRAK4:p-Pellino [cytosol] (Sus scrofa)
hp-IRAK1: p-Pellino-1,2,(3) [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
Interleukin-17 signaling (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
Innate Immune System (Sus scrofa)
Toll-like Receptor Cascades (Sus scrofa)
Toll Like Receptor 10 (TLR10) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
Toll Like Receptor 2 (TLR2) Cascade (Sus scrofa)
Toll Like Receptor TLR1:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
Toll Like Receptor TLR6:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
Toll Like Receptor 3 (TLR3) Cascade (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
Toll Like Receptor 4 (TLR4) Cascade (Sus scrofa)
MyD88-independent TLR4 cascade (Sus scrofa)
TRIF (TICAM1)-mediated TLR4 signaling (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
Toll Like Receptor 5 (TLR5) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
Toll Like Receptor 9 (TLR9) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
Activated TAK complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Sus scrofa)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:F1RZU1
Reference Genes
ENSEMBL:ENSSSCG00000012795.5
Other Identifiers
396606
GO:0000166
GO:0001959
GO:0002376
GO:0003824
GO:0004672
GO:0004674
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005886
GO:0007155
GO:0007165
GO:0007249
GO:0008063
GO:0009986
GO:0010033
GO:0016301
GO:0016740
GO:0019901
GO:0023052
GO:0031663
GO:0032481
GO:0032496
GO:0032991
GO:0034134
GO:0034142
GO:0035556
GO:0038172
GO:0042802
GO:0042803
GO:0043123
GO:0043226
GO:0045087
GO:0046982
GO:0048583
GO:0060337
GO:0070498
GO:0070555
GO:0070887
GO:0071222
GO:0098542
GO:0140096
GO:1904996
Ssc.19609.1.S1_at
Participates
as a component of
p-2S,S376,T,T209,T387-IRAK1:TRAF6 [cytosol] (Sus scrofa)
hp-IRAK1: p-Pellino-1,2,(3) [cytosol] (Sus scrofa)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1 [plasma membrane] (Sus scrofa)
hp-IRAK1: Pellino-1,2,3 [cytosol] (Sus scrofa)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Sus scrofa)
as a member of
p-2S,S376,T,T209,T387-IRAK1, IRAK4 [cytosol] (Sus scrofa)
Other forms of this molecule
phospho-K63polyUb-hp-IRAK1 [endosome membrane]
phospho-p-S376,T387-IRAK1 [cytosol]
phospho-p-S,T-IRAK1 [cytosol]
phospho-K63polyUb-hp-IRAK1 [cytosol]
phospho-p-2S,S376,T,T209,T387-IRAK1 [endosome membrane]
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane]
IRAK1 [cytosol]
Inferred From
p-2S,S376,T,T209,T387-IRAK1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 387 (in Homo sapiens)
Coordinate
387
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 376 (in Homo sapiens)
Coordinate
376
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 209 (in Homo sapiens)
Coordinate
209
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at unknown position
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at unknown position
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at unknown position
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
Ensembl
ENSSSCG00000012795
,
ENSSSCT00000013987
,
ENSSSCP00000013604
VGNC
89198
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text