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STAT3 [cytosol]
Stable Identifier
R-SSC-539044
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
STAT3, Q19S50
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
Signaling by Interleukins (Sus scrofa)
Interleukin-1 family signaling (Sus scrofa)
Interleukin-37 signaling (Sus scrofa)
STAT3 phosphorylation (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
Interleukin-10 signaling (Sus scrofa)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Sus scrofa)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3 [plasma membrane] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Sus scrofa)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3 [plasma membrane] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
Interleukin-12 family signaling (Sus scrofa)
Interleukin-23 signaling (Sus scrofa)
STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Sus scrofa)
IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2:STAT3:STAT4 [plasma membrane] (Sus scrofa)
IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2:STAT3 [plasma membrane] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
Interleukin-27 signaling (Sus scrofa)
STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Sus scrofa)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3 [plasma membrane] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
Interleukin-2 family signaling (Sus scrofa)
Interleukin-15 signaling (Sus scrofa)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5 (Sus scrofa)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:STAT3,STAT5,(STAT3:STAT5) [plasma membrane] (Sus scrofa)
STAT3,STAT5,(STAT3:STAT5) [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
STAT3:STAT5A,STAT5B [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
STAT3,STAT5,(STAT3:STAT5) [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
STAT3:STAT5A,STAT5B [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Sus scrofa)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:STAT3,STAT5,(STAT3:STAT5) [plasma membrane] (Sus scrofa)
STAT3,STAT5,(STAT3:STAT5) [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
STAT3:STAT5A,STAT5B [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
Interleukin-21 signaling (Sus scrofa)
IL21 receptor STAT binding (Sus scrofa)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3:STAT1,STAT3,STAT4,STAT5 [plasma membrane] (Sus scrofa)
STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
IL21 receptor STAT phosphorylation (Sus scrofa)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3:STAT1,STAT3,STAT4,STAT5 [plasma membrane] (Sus scrofa)
STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
Interleukin-9 signaling (Sus scrofa)
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B (Sus scrofa)
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane] (Sus scrofa)
STATs [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
STATs [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Sus scrofa)
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane] (Sus scrofa)
STATs [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
Interleukin-20 family signaling (Sus scrofa)
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Sus scrofa)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1,STAT2, STAT3, STAT4, STAT5 [plasma membrane] (Sus scrofa)
STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 (Sus scrofa)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1,STAT2, STAT3, STAT4, STAT5 [plasma membrane] (Sus scrofa)
STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Sus scrofa)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2:STAT3 [plasma membrane] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 binds STAT3 (Sus scrofa)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2:STAT3 [plasma membrane] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 (Sus scrofa)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 [plasma membrane] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Sus scrofa)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 [plasma membrane] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
Interleukin-4 and Interleukin-13 signaling (Sus scrofa)
JAK1 phosphorylates STAT3,STAT6 (Sus scrofa)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1:STAT3,STAT6 [plasma membrane] (Sus scrofa)
STAT3,STAT6 [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
STAT3,STAT6 bind p-Y-IL4R (Sus scrofa)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1:STAT3,STAT6 [plasma membrane] (Sus scrofa)
STAT3,STAT6 [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
STAT3,STAT6 [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
Interleukin-7 signaling (Sus scrofa)
STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Sus scrofa)
IL7R:TSLP:CRLF2:STAT3 [plasma membrane] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
Signaling by Non-Receptor Tyrosine Kinases (Sus scrofa)
Signaling by PTK6 (Sus scrofa)
PTK6 Activates STAT3 (Sus scrofa)
PTK6 phosphorylates STAT3 (Sus scrofa)
p-Y342-PTK6:p-Y250-STAP2:STAT3 [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
STAP2 recruits STAT3 to PTK6 (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
p-Y342-PTK6:p-Y250-STAP2:STAT3 [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by ALK (Sus scrofa)
STAT3 is phosphorylated downstream of active ALK (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
Signaling by PDGF (Sus scrofa)
Downstream signal transduction (Sus scrofa)
STAT binds to the active receptor (Sus scrofa)
PDGF:phospho-PDGF receptor dimer:STAT [plasma membrane] (Sus scrofa)
STAT family members [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
STAT family members [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
Signaling by SCF-KIT (Sus scrofa)
Phosphorylation of STATs (Sus scrofa)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Sus scrofa)
STATs [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
Recruitment of STATs (Sus scrofa)
STATs [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Sus scrofa)
STATs [cytosol] (Sus scrofa)
STAT3 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:Q19S50
Gene Names
STAT3
Reference Genes
BioGPS Gene:733648 STAT3
ENSEMBL:ENSSSCG00015062720
ENSEMBL:ENSSSCG00030068070 STAT3
ENSEMBL:ENSSSCG00040014380 STAT3
ENSEMBL:ENSSSCG00045038505 STAT3
ENSEMBL:ENSSSCG00060051919 STAT3
ENSEMBL:ENSSSCG00070014017 STAT3
KEGG Gene (Sus scrofa):733648 STAT3
Monarch:733648 STAT3
NCBI Gene:733648 STAT3
Reference Transcript
RefSeq:NM_001044580.1 STAT3
Participates
as a component of
IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2:STAT3 [plasma membrane] (Sus scrofa)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3 [plasma membrane] (Sus scrofa)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 [plasma membrane] (Sus scrofa)
IL7R:TSLP:CRLF2:STAT3 [plasma membrane] (Sus scrofa)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2:STAT3 [plasma membrane] (Sus scrofa)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3 [plasma membrane] (Sus scrofa)
STAT3:STAT5A,STAT5B [cytosol] (Sus scrofa)
p-Y342-PTK6:p-Y250-STAP2:STAT3 [cytosol] (Sus scrofa)
as an input of
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 (Sus scrofa)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 binds STAT3 (Sus scrofa)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Sus scrofa)
STAT3 is phosphorylated downstream of active ALK (Sus scrofa)
STAT3 phosphorylation (Sus scrofa)
STAP2 recruits STAT3 to PTK6 (Sus scrofa)
as a member of
STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Sus scrofa)
STAT3,STAT5,(STAT3:STAT5) [cytosol] (Sus scrofa)
STAT family members [cytosol] (Sus scrofa)
STATs [cytosol] (Sus scrofa)
STAT3,STAT6 [cytosol] (Sus scrofa)
Other forms of this molecule
phospho-STAT3 [nucleoplasm]
phospho-STAT3 [cytosol]
phospho-STAT3 [nucleoplasm]
phospho-STAT3 [nucleoplasm]
phospho-STAT3 [nucleoplasm]
phospho-STAT3 [cytosol]
phospho-STAT3 [cytosol]
phospho-STAT3 [cytosol]
phospho-STAT3 [nucleoplasm]
Inferred From
STAT1, STAT3 [cytosol]
(Homo sapiens)
STAT3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001038045.1
OpenTargets
ENSG00000168610
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