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TNFRSF6 [cytosol]
Stable Identifier
R-SSC-54639
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
FADD, Q56VC2
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Innate Immune System (Sus scrofa)
Toll-like Receptor Cascades (Sus scrofa)
Toll Like Receptor 4 (TLR4) Cascade (Sus scrofa)
MyD88-independent TLR4 cascade (Sus scrofa)
TRIF (TICAM1)-mediated TLR4 signaling (Sus scrofa)
TRIF-mediated programmed cell death (Sus scrofa)
Caspase-8 processing within TLR4 complex (Sus scrofa)
activated TLR4:TRIF:RIP1:FADD [endosome membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TLR4-induced ripoptosome assembly (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
Programmed Cell Death (Sus scrofa)
Apoptosis (Sus scrofa)
Caspase activation via extrinsic apoptotic signalling pathway (Sus scrofa)
Caspase activation via Death Receptors in the presence of ligand (Sus scrofa)
Caspase-8 processing within TLR4 complex (Sus scrofa)
activated TLR4:TRIF:RIP1:FADD [endosome membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
Dimerization of procaspase-8 (Sus scrofa)
FAS-mediated dimerization of procaspase-8 (Sus scrofa)
FASL:FAS receptor trimer:FADD:procaspase-8-dimer [plasma membrane] (Sus scrofa)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
FASL:FAS trimer:FADD:CASP8(1-479) [plasma membrane] (Sus scrofa)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TNF-mediated dimerization of procaspase-8 (Sus scrofa)
TRADD:TRAF2:RIP1:FADD:CASP8(1-479) [cytosol] (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TRAF2:TRADD:RIP1:FADD:2xCASP8(1-479) [cytosol] (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TRAIL-mediated dimerization of procaspase-8 (Sus scrofa)
TNFSF10:TNFRSF10A,B:FADD:2xCASP8(1-479) [plasma membrane] (Sus scrofa)
TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] (Sus scrofa)
TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
Regulation by c-FLIP (Sus scrofa)
Caspase-8 and FLIP(L) processing at DISC (Sus scrofa)
DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Sus scrofa)
DISC [plasma membrane] (Sus scrofa)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Sus scrofa)
DISC:procaspase-8 [plasma membrane] (Sus scrofa)
DISC [plasma membrane] (Sus scrofa)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
FLIP(L) and procaspase-8 form heterodimer in FasL/CD95 signaling (Sus scrofa)
FASL:FAS Receptor Trimer:FADD:pro-Caspase-8:FLIP(L) [plasma membrane] (Sus scrofa)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
FASL:FAS trimer:FADD:CASP8(1-479) [plasma membrane] (Sus scrofa)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Sus scrofa)
TRADD:TRAF2:RIP1:FADD:procaspase-8:FLIP(L) [cytosol] (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling (Sus scrofa)
TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] (Sus scrofa)
TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479):CFLAR [plasma membrane] (Sus scrofa)
TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
Regulated Necrosis (Sus scrofa)
RIPK1-mediated regulated necrosis (Sus scrofa)
Regulation of necroptotic cell death (Sus scrofa)
CASP8 activity is inhibited (Sus scrofa)
FLIP(L) and procaspase-8 form heterodimer (Sus scrofa)
DISC:procaspase-8 [plasma membrane] (Sus scrofa)
DISC [plasma membrane] (Sus scrofa)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Sus scrofa)
DISC:procaspase-8 [plasma membrane] (Sus scrofa)
DISC [plasma membrane] (Sus scrofa)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
FLIP(S) and procaspase-8 form heterodimer (Sus scrofa)
DISC:procaspase-8 [plasma membrane] (Sus scrofa)
DISC [plasma membrane] (Sus scrofa)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
DISC:procaspase-8:FLIP(S) [plasma membrane] (Sus scrofa)
DISC:procaspase-8 [plasma membrane] (Sus scrofa)
DISC [plasma membrane] (Sus scrofa)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
RIPK1 is cleaved by CASP8 (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
Death Receptor Signaling (Sus scrofa)
FasL/ CD95L signaling (Sus scrofa)
FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 (Sus scrofa)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
FASL:FAS trimer:FADD:CASP8(1-479) [plasma membrane] (Sus scrofa)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
FASL:FAS Receptor Trimer:FADD complex binds procaspase-10 (Sus scrofa)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
FASL:FAS Receptor Trimer:FADD:pro-Caspase-10 [plasma membrane] (Sus scrofa)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
FasL:Fas binds FADD (Sus scrofa)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TNF signaling (Sus scrofa)
Regulation of TNFR1 signaling (Sus scrofa)
Caspase-8 and FLIP(L) processing at TNFR signaling complex (Sus scrofa)
TRADD:TRAF2:RIP1:FADD:procaspase-8:FLIP(L) [cytosol] (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Sus scrofa)
TRADD:TRAF2:RIP1:FADD:procaspase-8:FLIP(L) [cytosol] (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
RIPK1 is cleaved by CASP8 (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
RIPK1 is cleaved by CASP8:FLIP(L) (Sus scrofa)
TRADD:TRAF2:RIPK1(325-671):FADD:p43/p41CASP8:p43 FLIP(L) [cytosol] (Sus scrofa)
TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TNFR1-induced proapoptotic signaling (Sus scrofa)
TRADD:TRAF2:RIP1 binds FADD (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Sus scrofa)
TNFRSF6 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:Q56VC2
Gene Names
TNFRSF6
Reference Genes
BioGPS Gene:595129 TNFRSF6
ENSEMBL:ENSSSCG00000054981.1
KEGG:ssc:595129 TNFRSF6
Monarch:595129 TNFRSF6
NCBI Gene:595129 TNFRSF6
UCSC:Q56VC2 TNFRSF6
Reference Transcript
RefSeq:NM_001031797.1 TNFRSF6
Other Identifiers
595129
GO:0001916
GO:0002020
GO:0002376
GO:0002821
GO:0005123
GO:0005737
GO:0005829
GO:0005886
GO:0006351
GO:0006355
GO:0006915
GO:0007155
GO:0007165
GO:0008625
GO:0012501
GO:0023052
GO:0030154
GO:0031264
GO:0031265
GO:0032729
GO:0032757
GO:0032760
GO:0032813
GO:0033077
GO:0035591
GO:0035877
GO:0036462
GO:0042104
GO:0042802
GO:0042981
GO:0043029
GO:0043065
GO:0043123
GO:0045087
GO:0045089
GO:0045651
GO:0045862
GO:0045944
GO:0048535
GO:0048536
GO:0048538
GO:0048856
GO:0048870
GO:0051607
GO:0060090
GO:0060340
GO:0060546
GO:0065003
GO:0070236
GO:0071260
GO:0071550
GO:0089720
GO:0097049
GO:0097190
GO:0097191
GO:0097192
GO:0097342
GO:0097527
GO:0098542
GO:1900119
GO:2000454
GO:2001238
Ssc.1947.1.S1_at
Ssc.1947.2.S1_at
Ssc.25123.1.A1_at
Participates
as a component of
TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] (Sus scrofa)
TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Sus scrofa)
FASL:FAS Receptor Trimer:FADD [plasma membrane] (Sus scrofa)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Sus scrofa)
activated TLR4:TRIF:RIP1:FADD [endosome membrane] (Sus scrofa)
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Sus scrofa)
as an input of
FasL:Fas binds FADD (Sus scrofa)
TRADD:TRAF2:RIP1 binds FADD (Sus scrofa)
TLR4-induced ripoptosome assembly (Sus scrofa)
Inferred From
FADD [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001026967.1
ENSEMBL
ENSSSCG00000054981
,
ENSSSCP00000075653
,
ENSSSCT00000105894
VGNC
87874
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