Reactome | FOLR1 [ER to Golgi transport vesicle membrane]

FOLR1 [ER to Golgi transport vesicle membrane]

Stable Identifier

R-SSC-5689806

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

ER to Golgi transport vesicle membrane

Synonyms

GPI-FOLR1, A0A287BLX2

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Sus scrofa)

- Post-translational protein modification (Sus scrofa)
  - Asparagine N-linked glycosylation (Sus scrofa)
    - Transport to the Golgi and subsequent modification (Sus scrofa)
      - ER to Golgi Anterograde Transport (Sus scrofa)
        
        COPII-mediated vesicle transport (Sus scrofa)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Sus scrofa)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        Nucleotide exchange on RAB1 (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        Vesicle budding (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)

Vesicle-mediated transport (Sus scrofa)

- Membrane Trafficking (Sus scrofa)
  - ER to Golgi Anterograde Transport (Sus scrofa)
    - COPII-mediated vesicle transport (Sus scrofa)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Sus scrofa)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
      - Nucleotide exchange on RAB1 (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
      - RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
      - Vesicle budding (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287BLX2

Gene Names

FOLR1

Reference Genes

BioGPS Gene:396784 FOLR1

ENSEMBL:ENSSSCG00000022236.4

Monarch:396784 FOLR1

NCBI Gene:396784 FOLR1

Reference Transcript

RefSeq:XM_013999144.1 FOLR1

Other Identifiers

396784

GO:0005886

GO:0007155

GO:0007342

GO:0009897

GO:0022414

GO:0035036

GO:0038023

GO:0060089

GO:0061024

Ssc.11779.1.S1_at

Participates

as a member of

GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)

Other forms of this molecule

FOLR1 [endoplasmic reticulum membrane]

FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

FOLR1 [transport vesicle]

FOLR1 [Golgi membrane]

Inferred From

GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Homo sapiens)

Modified Residues

Name

L-serine amide (GPI-anchor amidated amino acid carboxyl end residue(1−)) at 201 (in Homo sapiens)

Coordinate

201

Modification

GPI-anchor amidated amino acid carboxyl end residue(1−)

PsiMod Name

L-serine amide

PsiMod Definition

A protein modification that effectively converts an L-serine residue to L-serine amide.

Cross References

RefSeq

XP_013854598.1

OpenTargets

ENSG00000110195

Ensembl

ENSSSCG00000022236, ENSSSCP00000057418, ENSSSCT00000053637

VGNC

108156

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