Reactome | NDUFA3 [mitochondrial inner membrane]

NDUFA3 [mitochondrial inner membrane]

Stable Identifier

R-SSC-60180

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

mitochondrial inner membrane

Synonyms

F1RNI5

Locations in the PathwayBrowser

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Metabolism (Sus scrofa)

- Aerobic respiration and respiratory electron transport (Sus scrofa)
  - Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Sus scrofa)
    - Respiratory electron transport (Sus scrofa)
      - Complex I biogenesis (Sus scrofa)
        
        Intermediate 1 binds HP subcomplex to form Intermediate 2 (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA3 [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA3 [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA3 [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA3 [mitochondrial inner membrane] (Sus scrofa)
        
        ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA3 [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA3 [mitochondrial inner membrane] (Sus scrofa)
        
        Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Sus scrofa)
        
        815kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA3 [mitochondrial inner membrane] (Sus scrofa)
        
        980kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA3 [mitochondrial inner membrane] (Sus scrofa)
        
        The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA3 [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA3 [mitochondrial inner membrane] (Sus scrofa)
        
        The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Sus scrofa)
        
        980kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA3 [mitochondrial inner membrane] (Sus scrofa)
        
        Complex I [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA3 [mitochondrial inner membrane] (Sus scrofa)
      - Complex I oxidises NADH to NAD+, reduces CoQ to QH2 (Sus scrofa)
        
        Complex I [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA3 [mitochondrial inner membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RNI5

Reference Genes

ENSEMBL:ENSSSCG00000003261.4

ENSEMBL:ENSSSCG00005037608.1

Other Identifiers

100520312

GO:0005739

GO:0005743

GO:0005747

GO:0016020

GO:0043226

GO:0070469

Ssc.20956.1.S1_at

Participates

as a component of

HP subcomplex [mitochondrial inner membrane] (Sus scrofa)

Inferred From

NDUFA3 [mitochondrial inner membrane] (Homo sapiens)

Cross References

Ensembl

ENSSSCG00000003261, ENSSSCT00000003622, ENSSSCP00000003537

PDB

7V2K, 5GPN, 7V2D, 7V3M, 7V2C, 7V30, 7VY1, 7V2R, 7VBP, 7VC0, 7V2F, 7V2H, 7V33, 5GUP, 7V32, 7VBL, 7VWL, 7V2E, 7V31

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