Reactome | WRN [nucleoplasm]

WRN [nucleoplasm]

Stable Identifier

R-SSC-67387

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

WRN, F1RX70

Locations in the PathwayBrowser

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Cell Cycle (Sus scrofa)

- Cell Cycle Checkpoints (Sus scrofa)
  - G2/M Checkpoints (Sus scrofa)
    - G2/M DNA damage checkpoint (Sus scrofa)
      - ATR phosphorylates TP53 (Sus scrofa)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
- Chromosome Maintenance (Sus scrofa)
  - Telomere Maintenance (Sus scrofa)
    - Extension of Telomeres (Sus scrofa)
      - Telomere C-strand (Lagging Strand) Synthesis (Sus scrofa)
        
        Processive synthesis on the C-strand of the telomere (Sus scrofa)
        
        Formation of the Flap Intermediate on the C-strand (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        Removal of the Flap Intermediate from the C-strand (Sus scrofa)
        
        Removal of remaining Flap from the C-strand (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)

DNA Repair (Sus scrofa)

- DNA Double-Strand Break Repair (Sus scrofa)
  - Homology Directed Repair (Sus scrofa)
    - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Sus scrofa)
      - HDR through Homologous Recombination (HRR) (Sus scrofa)
        
        D-loop extension by DNA polymerases (Sus scrofa)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        Homologous DNA Pairing and Strand Exchange (Sus scrofa)
        
        CX3 complex binds D-loop structures (Sus scrofa)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        D-loop formation mediated by PALB2, BRCA2 and RAD51 (Sus scrofa)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1:BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        Presynaptic phase of homologous DNA pairing and strand exchange (Sus scrofa)
        
        BCDX2 complex stabilizes RAD51 filament (Sus scrofa)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1:BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        Resolution of D-Loop Structures (Sus scrofa)
        
        Resolution of D-loop Structures through Holliday Junction Intermediates (Sus scrofa)
        
        Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Sus scrofa)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        Ligation of DNA and formation of Holliday structures following repair synthesis (Sus scrofa)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        MUS81:EME1,EME2 cleaves D-loop (Sus scrofa)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
      - HDR through Single Strand Annealing (SSA) (Sus scrofa)
        
        Association of RAD51 with RAD52:DNA double-strand break ends (Sus scrofa)
        
        RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        Association of RAD52 with the RPA complex at resected DNA DSBs (Sus scrofa)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        ERCC1:XPF cleaves flaps generated by SSA (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        RAD52 promotes single strand annealing at resected DNA DSBs (Sus scrofa)
        
        RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
      - Processing of DNA double-strand break ends (Sus scrofa)
        
        ATR activation at DNA DSBs (Sus scrofa)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        ATR phosphorylates RPA2 (Sus scrofa)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        Activation of CHEK1 at resected DNA DSBs (Sus scrofa)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        Association of RPA complexes with ssDNA at resected DNA DSBs (Sus scrofa)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        Binding of ATR:ATRIP to RPA at resected DNA DSBs (Sus scrofa)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        CHEK1 is recruited to resected DNA DSBs (Sus scrofa)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment (Sus scrofa)
        
        3' short overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        Long-range resection of DNA DSBs by EXO1 or DNA2 (Sus scrofa)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        3' short overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)

Gene expression (Transcription) (Sus scrofa)

- RNA Polymerase II Transcription (Sus scrofa)
  - Generic Transcription Pathway (Sus scrofa)
    - Transcriptional Regulation by TP53 (Sus scrofa)
      - Regulation of TP53 Activity (Sus scrofa)
        
        Regulation of TP53 Activity through Phosphorylation (Sus scrofa)
        
        ATR phosphorylates TP53 (Sus scrofa)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Sus scrofa)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Sus scrofa)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        DNA2:WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)
        
        EXO1:BLM,WRN [nucleoplasm] (Sus scrofa)
        
        BLM,WRN [nucleoplasm] (Sus scrofa)
        
        WRN [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RX70

Gene Names

WRN

Reference Genes

ENSEMBL:ENSSSCG00000015840.5

Other Identifiers

100512139

GO:0000166

GO:0000287

GO:0000400

GO:0000403

GO:0000405

GO:0000723

GO:0000724

GO:0000731

GO:0000781

GO:0003676

GO:0003677

GO:0003678

GO:0003824

GO:0004386

GO:0004527

GO:0005524

GO:0005634

GO:0005654

GO:0005694

GO:0005730

GO:0005737

GO:0005813

GO:0005815

GO:0005856

GO:0006139

GO:0006259

GO:0006260

GO:0006268

GO:0006281

GO:0006284

GO:0006302

GO:0006310

GO:0006974

GO:0006979

GO:0008408

GO:0009267

GO:0009378

GO:0010225

GO:0016607

GO:0016787

GO:0016887

GO:0030145

GO:0031297

GO:0032200

GO:0032392

GO:0032405

GO:0032508

GO:0042803

GO:0043138

GO:0043226

GO:0044237

GO:0044806

GO:0044877

GO:0051880

GO:0061749

GO:0061820

GO:0061821

GO:0061849

GO:0070337

GO:0071480

GO:0090398

GO:0098530

GO:0140097

GO:0140657

GO:1902570

GO:1905773

Participates

as a member of

BLM,WRN [nucleoplasm] (Sus scrofa)

as a candidate of

BLM,WRN [nucleoplasm] (Sus scrofa)

as a component of

DNA2:WRN [nucleoplasm] (Sus scrofa)

This entity regulates

Positively

Removal of remaining Flap from the C-strand (Sus scrofa)

Other forms of this molecule

WRN [nucleoplasm]

Inferred From

WRN [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000165392

Ensembl

ENSSSCP00000016786, ENSSSCG00000015840, ENSSSCT00000017248

VGNC

96605

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