Reactome | HSPA1A [nucleoplasm]

HSPA1A [nucleoplasm]

Stable Identifier

R-SSC-6792605

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

A0A287BQU9

Locations in the PathwayBrowser

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Cellular responses to stimuli (Sus scrofa)

- Cellular responses to stress (Sus scrofa)
  - Cellular response to heat stress (Sus scrofa)
    - HSF1-dependent transactivation (Sus scrofa)
      - Attenuation phase (Sus scrofa)
        
        HSF1 acetylation at Lys80 (Sus scrofa)
        
        HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] (Sus scrofa)
        
        HSP70:DNAJB1 [nucleoplasm] (Sus scrofa)
        
        HSPA (HSP70) proteins [nucleoplasm] (Sus scrofa)
        
        Homologues of HSPA1A [nucleoplasm] (Sus scrofa)
        
        HSPA1A [nucleoplasm] (Sus scrofa)
        
        HSP70:DNAJB1:HSF1 trimer:target gene [nucleoplasm] (Sus scrofa)
        
        HSP70:DNAJB1 [nucleoplasm] (Sus scrofa)
        
        HSPA (HSP70) proteins [nucleoplasm] (Sus scrofa)
        
        Homologues of HSPA1A [nucleoplasm] (Sus scrofa)
        
        HSPA1A [nucleoplasm] (Sus scrofa)
        
        HSP70:DNAJB1 binds HSF1 (Sus scrofa)
        
        HSP70:DNAJB1 [nucleoplasm] (Sus scrofa)
        
        HSPA (HSP70) proteins [nucleoplasm] (Sus scrofa)
        
        Homologues of HSPA1A [nucleoplasm] (Sus scrofa)
        
        HSPA1A [nucleoplasm] (Sus scrofa)
        
        HSP70:DNAJB1:HSF1 trimer:target gene [nucleoplasm] (Sus scrofa)
        
        HSP70:DNAJB1 [nucleoplasm] (Sus scrofa)
        
        HSPA (HSP70) proteins [nucleoplasm] (Sus scrofa)
        
        Homologues of HSPA1A [nucleoplasm] (Sus scrofa)
        
        HSPA1A [nucleoplasm] (Sus scrofa)
      - HSF1-mediated gene expression (Sus scrofa)
        
        Heat shock inducible proteins [nucleoplasm] (Sus scrofa)
        
        Homologues of HSPA1A [nucleoplasm] (Sus scrofa)
        
        HSPA1A [nucleoplasm] (Sus scrofa)
    - Regulation of HSF1-mediated heat shock response (Sus scrofa)
      - HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm (Sus scrofa)
        
        HSP70s:ADP [nucleoplasm] (Sus scrofa)
        
        HSPA1A:ADP [nucleoplasm] (Sus scrofa)
        
        Homologues of HSPA1A [nucleoplasm] (Sus scrofa)
        
        HSPA1A [nucleoplasm] (Sus scrofa)
        
        Hikeshi:HSP70s:ATP [nucleoplasm] (Sus scrofa)
        
        HSP70s:ATP [nucleoplasm] (Sus scrofa)
        
        HSPA1A:ATP [nucleoplasm] (Sus scrofa)
        
        Homologues of HSPA1A [nucleoplasm] (Sus scrofa)
        
        HSPA1A [nucleoplasm] (Sus scrofa)
      - NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm (Sus scrofa)
        
        Hikeshi:HSP70s:ATP [nucleoplasm] (Sus scrofa)
        
        HSP70s:ATP [nucleoplasm] (Sus scrofa)
        
        HSPA1A:ATP [nucleoplasm] (Sus scrofa)
        
        Homologues of HSPA1A [nucleoplasm] (Sus scrofa)
        
        HSPA1A [nucleoplasm] (Sus scrofa)
      - SIRT1 binds to HSF1 (Sus scrofa)
        
        HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] (Sus scrofa)
        
        HSP70:DNAJB1 [nucleoplasm] (Sus scrofa)
        
        HSPA (HSP70) proteins [nucleoplasm] (Sus scrofa)
        
        Homologues of HSPA1A [nucleoplasm] (Sus scrofa)
        
        HSPA1A [nucleoplasm] (Sus scrofa)
        
        SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] (Sus scrofa)
        
        HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] (Sus scrofa)
        
        HSP70:DNAJB1 [nucleoplasm] (Sus scrofa)
        
        HSPA (HSP70) proteins [nucleoplasm] (Sus scrofa)
        
        Homologues of HSPA1A [nucleoplasm] (Sus scrofa)
        
        HSPA1A [nucleoplasm] (Sus scrofa)
      - SIRT1 deacetylates HSF1 (Sus scrofa)
        
        HSP70:DNAJB1:HSF1 trimer:target gene [nucleoplasm] (Sus scrofa)
        
        HSP70:DNAJB1 [nucleoplasm] (Sus scrofa)
        
        HSPA (HSP70) proteins [nucleoplasm] (Sus scrofa)
        
        Homologues of HSPA1A [nucleoplasm] (Sus scrofa)
        
        HSPA1A [nucleoplasm] (Sus scrofa)
        
        SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] (Sus scrofa)
        
        HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] (Sus scrofa)
        
        HSP70:DNAJB1 [nucleoplasm] (Sus scrofa)
        
        HSPA (HSP70) proteins [nucleoplasm] (Sus scrofa)
        
        Homologues of HSPA1A [nucleoplasm] (Sus scrofa)
        
        HSPA1A [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287BQU9

Reference Genes

ENSEMBL:ENSSSCG00000029160.4

Other Identifiers

GO:0000166

GO:0000278

GO:0003824

GO:0005524

GO:0005634

GO:0005737

GO:0006457

GO:0007010

GO:0007059

GO:0016787

GO:0016887

GO:0030163

GO:0031072

GO:0031625

GO:0032436

GO:0042026

GO:0043226

GO:0044183

GO:0051085

GO:0140014

GO:0140657

GO:0140662

GO:1901673

Ssc.5145.1.S1_a_at

Ssc.5145.1.S1_at

Participates

as a member of

Homologues of HSPA1A [nucleoplasm] (Sus scrofa)

Other forms of this molecule

HSPA1A [cytosol]

HSPA1A [extracellular region]

HSPA1A [ficolin-1-rich granule lumen]

Inferred From

HSPA1B [nucleoplasm] (Homo sapiens)

HSPA1A [nucleoplasm] (Homo sapiens)

Cross References

Ensembl

ENSSSCT00000026311, ENSSSCG00000029160, ENSSSCP00000058891

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