Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
CCNK [nucleoplasm]
Stable Identifier
R-SSC-6796619
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
nucleoplasm
Synonyms
CCNK, F1SAQ3
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional Regulation by TP53 (Sus scrofa)
TP53 Regulates Transcription of DNA Repair Genes (Sus scrofa)
CCNK binds CDK12 (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
CCNK:CDK12 [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
CCNK binds CDK13 (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
CCNK:CDK13 [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
CCNK:CDK12 binds RNA Pol II at DNA repair genes (Sus scrofa)
CCNK:CDK12 [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Sus scrofa)
CCNK:CDK12 [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Sus scrofa)
CCNK:CDK12 [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes [nucleoplasm] (Sus scrofa)
CCNK:CDK12 [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Sus scrofa)
CDK12-phosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Sus scrofa)
CCNK:CDK12 [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Sus scrofa)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Sus scrofa)
Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Sus scrofa)
CDK8:CCNC/ CDK9:CCNT [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
RNA Polymerase II Pre-transcription Events (Sus scrofa)
2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Sus scrofa)
Paused processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Abortive termination of elongation after arrest (Sus scrofa)
Aborted elongation complex after arrest [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Elongating transcript encounters a lesion in the template (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Formation of P-TEFb complex (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Resumption of elongation after recovery from pausing (Sus scrofa)
Paused processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
TFIIS-mediated recovery of elongation from arrest (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
RNA Polymerase II Transcription Elongation (Sus scrofa)
Addition of nucleotides leads to transcript elongation (Sus scrofa)
Elongation complex [nucleoplasm] (Sus scrofa)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Formation of RNA Pol II elongation complex (Sus scrofa)
Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex (Sus scrofa)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Recruitment of elongation factors to form elongation complex (Sus scrofa)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Elongation complex [nucleoplasm] (Sus scrofa)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Pol II elongation complex moves on the template as transcript elongates (Sus scrofa)
Elongation complex prior to separation [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Separation of elongating transcript from template (Sus scrofa)
Elongation complex prior to separation [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Elongation complex with separated and uncleaved transcript [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
RNA polymerase II transcribes snRNA genes (Sus scrofa)
CBCAP complex binds 7-methylguanosine cap of snRNA (Sus scrofa)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Sus scrofa)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Sus scrofa)
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Integrator complex processes the 3' end of snRNA (Sus scrofa)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Pre-snRNA is elongated and capped with 7-methylguanosine (Sus scrofa)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Pre-snRNA transcript initiation, Integrator binding, LEC binding (Sus scrofa)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Sus scrofa)
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Sus scrofa)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
Signal Transduction (Sus scrofa)
Signaling by TGFB family members (Sus scrofa)
Signaling by TGF-beta Receptor Complex (Sus scrofa)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Sus scrofa)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Sus scrofa)
Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Sus scrofa)
CDK8:CCNC/ CDK9:CCNT [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
CCNK [nucleoplasm] (Sus scrofa)
External Reference Information
External Reference
UniProt:F1SAQ3
Gene Names
CCNK
Reference Genes
ENSEMBL:ENSSSCG00000002509
Other Identifiers
100157799
GO:0002944
GO:0002945
GO:0003674
GO:0004693
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0006357
GO:0006464
GO:0006950
GO:0006974
GO:0007049
GO:0007165
GO:0008024
GO:0008150
GO:0008353
GO:0009058
GO:0009966
GO:0016301
GO:0016538
GO:0019899
GO:0019901
GO:0030234
GO:0032786
GO:0032968
GO:0032991
GO:0034641
GO:0043226
GO:0044403
GO:0044828
GO:0045737
GO:0050790
GO:0051726
GO:0061575
GO:0070816
GO:2001165
Participates
as an input of
CCNK binds CDK13 (Sus scrofa)
CCNK binds CDK12 (Sus scrofa)
as a component of
CCNK:CDK13 [nucleoplasm] (Sus scrofa)
CCNK:CDK12 [nucleoplasm] (Sus scrofa)
as a member of
CCNT1,CCNT2,CCNK [nucleoplasm] (Sus scrofa)
Inferred From
CCNK [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000090061
Ensembl
ENSSSCT00000002787
,
ENSSSCP00000002716
,
ENSSSCG00000002509
VGNC
86362
© 2022
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
