Reactome | DSG4 [plasma membrane]

DSG4 [plasma membrane]

Stable Identifier

R-SSC-6814743

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

DSG4, I3L5R5

Locations in the PathwayBrowser

Expand all

Developmental Biology (Sus scrofa)

- Keratinization (Sus scrofa)
  - Formation of the cornified envelope (Sus scrofa)
    - Fillagrin and keratin intermediate filaments polymerize forming a network (Sus scrofa)
      - FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG4 [plasma membrane] (Sus scrofa)
      - FLG-Keratin filament network [plasma membrane] (Sus scrofa)
        
        FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG4 [plasma membrane] (Sus scrofa)
    - PERP binds desmosomes (Sus scrofa)
      - Desmosome [plasma membrane] (Sus scrofa)
        
        Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG4 [plasma membrane] (Sus scrofa)
      - Desmosome:PERP [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG4 [plasma membrane] (Sus scrofa)
    - Plasma membrane resorption (Sus scrofa)
      - Mature cornified envelope [plasma membrane] (Sus scrofa)
        
        No FGN-cornified envelope:CDSN [plasma membrane] (Sus scrofa)
        
        No FGN-Cornified envelope [plasma membrane] (Sus scrofa)
        
        No FGN-late cornified envelope [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome network [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG4 [plasma membrane] (Sus scrofa)
  - Keratin filaments bind cell-cell adhesion complexes (Sus scrofa)
    - Desmosome [plasma membrane] (Sus scrofa)
      - Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG4 [plasma membrane] (Sus scrofa)
    - Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
      - Desmosome [plasma membrane] (Sus scrofa)
        
        Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG4 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:I3L5R5

Gene Names

DSG4

Reference Genes

BioGPS Gene:100626137 DSG4

ENSEMBL:ENSSSCG00000020740.4

KEGG Gene (Sus scrofa):100626137 DSG4

Monarch:100626137 DSG4

NCBI Gene:100626137 DSG4

Reference Transcript

RefSeq:XM_003356395.3 DSG4

Other Identifiers

100626137

GO:0001942

GO:0005509

GO:0005886

GO:0007155

GO:0007156

GO:0016020

GO:0023052

GO:0030057

GO:0030154

GO:0030216

GO:0030509

GO:0048856

GO:0070161

GO:0098609

Participates

as a member of

Desmogelins [plasma membrane] (Sus scrofa)

Other forms of this molecule

DSG4 [cornified envelope]

Inferred From

DSG4 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_003356443.3

OpenTargets

ENSG00000175065

Ensembl

ENSSSCG00000020740, ENSSSCT00000032052, ENSSSCP00000019365

VGNC

87458

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