Reactome | RPRD1A [nucleoplasm]

RPRD1A [nucleoplasm]

Stable Identifier

R-SSC-6814899

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

RPRD1A, A0A5G2R2S7

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Sus scrofa)

- RNA Polymerase II Transcription (Sus scrofa)
  - RNA polymerase II transcribes snRNA genes (Sus scrofa)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A [nucleoplasm] (Sus scrofa)
    - Integrator complex processes the 3' end of snRNA (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A [nucleoplasm] (Sus scrofa)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A [nucleoplasm] (Sus scrofa)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Sus scrofa)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A [nucleoplasm] (Sus scrofa)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RPRD1A,B:RPRD2:RPAP2 [nucleoplasm] (Sus scrofa)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A [nucleoplasm] (Sus scrofa)
    - RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Sus scrofa)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RPRD1A,B:RPRD2:RPAP2 [nucleoplasm] (Sus scrofa)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A [nucleoplasm] (Sus scrofa)
      - RPRD1A,B:RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A,B [nucleoplasm] (Sus scrofa)
        
        RPRD1A [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A5G2R2S7

Gene Names

RPRD1A

Reference Genes

ENSEMBL:ENSSSCG00000027700

Other Identifiers

100621319

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0006464

GO:0008150

GO:0009058

GO:0016591

GO:0032991

GO:0034641

GO:0043226

GO:0070940

Ssc.21424.1.A1_at

Ssc.21711.1.A1_at

Participates

as a member of

RPRD1A,B [nucleoplasm] (Sus scrofa)

Inferred From

RPRD1A [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000141425

Ensembl

ENSSSCG00000027700, ENSSSCP00000064849, ENSSSCT00000087017

VGNC

92435

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