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phospho-p-T177-CDK6 [nucleoplasm]
Stable Identifier
R-SSC-69628
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
nucleoplasm
Synonyms
K7GT60
Locations in the PathwayBrowser
Expand all
Cell Cycle (Sus scrofa)
Cell Cycle, Mitotic (Sus scrofa)
Mitotic G1 phase and G1/S transition (Sus scrofa)
G1 Phase (Sus scrofa)
Cyclin D associated events in G1 (Sus scrofa)
CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND1 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND2 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND3 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND1 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND2 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND3 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND1 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND2 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND3 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND:CDK6 inhibitors [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND1:CDK6 inhibitors (CCND1) [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND1 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND2:CDK6 inhibitors (CCND2) [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND2 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND3:CDK6 inhibitors (CCND3) [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND3 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND1 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND2 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND3 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
Drug-mediated inhibition of CDK4/CDK6 activity (Sus scrofa)
CDK6 inhibitors bind CDK6 (Sus scrofa)
p-T177-CDK6:CCND [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND1 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND2 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND3 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND:CDK6 inhibitors [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND1:CDK6 inhibitors (CCND1) [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND1 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND2:CDK6 inhibitors (CCND2) [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND2 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND3:CDK6 inhibitors (CCND3) [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND3 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6:CCND [nucleoplasm] (Sus scrofa)
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND1 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND2 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND3 [nucleoplasm] (Sus scrofa)
phospho-p-T177-CDK6 [nucleoplasm] (Sus scrofa)
External Reference Information
External Reference
UniProt:K7GT60
Reference Genes
ENSEMBL:ENSSSCG00000040183.2
ENSEMBL:ENSSSCG00005042416.1
Reference Transcript
RefSeq:XM_013979690.1
Other Identifiers
GO:0000082
GO:0000166
GO:0000278
GO:0000307
GO:0001726
GO:0001954
GO:0002376
GO:0003323
GO:0003824
GO:0004672
GO:0004674
GO:0004693
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0007155
GO:0009615
GO:0010468
GO:0016740
GO:0030154
GO:0030332
GO:0042063
GO:0042127
GO:0043226
GO:0043697
GO:0045638
GO:0045646
GO:0045656
GO:0045668
GO:0045786
GO:0048146
GO:0048856
GO:0050680
GO:0051726
GO:0098770
GO:0140096
GO:2000773
Ssc.25289.1.S1_at
Ssc.26057.1.A1_at
Participates
as a component of
p-T177-CDK6:CCND3 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND2 [nucleoplasm] (Sus scrofa)
p-T177-CDK6:CCND1 [nucleoplasm] (Sus scrofa)
as a candidate of
p-T172-CDK4,p-T177-CDK6 [nucleoplasm] (Sus scrofa)
Other forms of this molecule
CDK6 [cytosol]
CDK6 [nucleoplasm]
Inferred From
p-T177-CDK6 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 177 (in Homo sapiens)
Coordinate
177
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
XP_013835144.1
Ensembl
ENSSSCG00000040183
,
ENSSSCT00000035327
,
ENSSSCP00000030626
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