Reactome | SNAPC5 [nucleoplasm]

SNAPC5 [nucleoplasm]

Stable Identifier

R-SSC-83724

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

SNAPC5, A0A286ZWK5

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Sus scrofa)

- RNA Polymerase II Transcription (Sus scrofa)
  - RNA polymerase II transcribes snRNA genes (Sus scrofa)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC5 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC5 [nucleoplasm] (Sus scrofa)
    - CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Sus scrofa)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC5 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC5 [nucleoplasm] (Sus scrofa)
    - Integrator complex processes the 3' end of snRNA (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC5 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC5 [nucleoplasm] (Sus scrofa)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC5 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC5 [nucleoplasm] (Sus scrofa)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Sus scrofa)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC5 [nucleoplasm] (Sus scrofa)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC5 [nucleoplasm] (Sus scrofa)
    - RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Sus scrofa)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC5 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC5 [nucleoplasm] (Sus scrofa)
    - RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Sus scrofa)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC5 [nucleoplasm] (Sus scrofa)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC5 [nucleoplasm] (Sus scrofa)
- RNA Polymerase III Transcription (Sus scrofa)
  - RNA Polymerase III Transcription Initiation (Sus scrofa)
    - RNA Polymerase III Transcription Initiation From Type 3 Promoter (Sus scrofa)
      - Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex (Sus scrofa)
        
        RNA Polymerase III:TFIIIB:SNAPc:Type 3 Promoter Complex [nucleoplasm] (Sus scrofa)
        
        TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Sus scrofa)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC5 [nucleoplasm] (Sus scrofa)
        
        TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Sus scrofa)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC5 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A286ZWK5

Gene Names

SNAPC5

Reference Genes

BioGPS Gene:100157710 SNAPC5

ENSEMBL:ENSSSCG00000038941

KEGG Gene (Sus scrofa):100157710 SNAPC5

Monarch:100157710 SNAPC5

NCBI Gene:100157710 SNAPC5

Reference Transcript

Other Identifiers

100157710

GO:0000995

GO:0003674

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005730

GO:0006366

GO:0006384

GO:0008150

GO:0009058

GO:0016251

GO:0016604

GO:0034641

GO:0042795

GO:0042796

GO:0043226

Participates

as a component of

SNAPc [nucleoplasm] (Sus scrofa)

Inferred From

SNAPC5 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_005659918.1, NP_001230607.1, XP_013848765.1

OpenTargets

ENSG00000174446

Ensembl

ENSSSCP00000035890, ENSSSCT00000051828, ENSSSCG00000038941

VGNC

93283

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