Reactome | IFNA2 [extracellular region]

IFNA2 [extracellular region]

Stable Identifier

R-SSC-877349-4

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

extracellular region

Synonyms

A0A8W4F7R3

Locations in the PathwayBrowser

Expand all

Immune System (Sus scrofa)

- Cytokine Signaling in Immune system (Sus scrofa)
  - Interferon Signaling (Sus scrofa)
    - Interferon alpha/beta signaling (Sus scrofa)
      - Activation of JAK kinases (Sus scrofa)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Sus scrofa)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
        
        p-TYK2:p-IFNAR1:SOCS-1/SOCS-3:IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
      - Formation of p-STAT1 homodimer (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
      - IFN alpha/beta binds to IFNAR2 (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
      - Phosphorylation of INFAR1 by TYK2 (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
      - Phosphorylation of STAT2 (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
      - Recruitment of IFNAR1 (Sus scrofa)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Sus scrofa)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
      - Recruitment of STAT2 to p-IFNAR1 (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
      - Regulation of IFNA/IFNB signaling (Sus scrofa)
        
        Dephosphorylation of JAK1 by SHP1 (Sus scrofa)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Sus scrofa)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
        
        Dephosphorylation of STAT1 by SHP2 (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:STAT1 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
        
        Dephosphorylation of TYK2 by PTP1B (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
      - Release of p-STAT2:p-STAT1 dimer (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Sus scrofa)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Sus scrofa)
        
        IFNA [extracellular region] (Sus scrofa)
        
        Homologues of IFNA2 [extracellular region] (Sus scrofa)
        
        IFNA2 [extracellular region] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A8W4F7R3

Reference Genes

ENSEMBL:ENSSSCG00000038797.2

Other Identifiers

GO:0005125

GO:0005126

GO:0005576

GO:0005615

GO:0006952

GO:0007165

GO:0023052

GO:0048018

GO:0051607

GO:0098542

GO:0098772

Ssc.19264.1.S1_at

Participates

as a member of

Homologues of IFNA2 [extracellular region] (Sus scrofa)

Other forms of this molecule

IFNA1 [extracellular region]

Inferred From

IFNA2 [extracellular region] (Homo sapiens)

Cross References

Ensembl

ENSSSCG00000038797, ENSSSCT00000057587, ENSSSCP00000075321

Cite Us!