Reactome | THOC5 [nucleoplasm]

THOC5 [nucleoplasm]

Stable Identifier

R-SSC-8849111

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

THOC5, A0A287AR63

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Sus scrofa)

- RNA Polymerase II Transcription (Sus scrofa)
  - RNA Polymerase II Transcription Termination (Sus scrofa)
    - Cleavage of mRNA at the 3'-end (Sus scrofa)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Sus scrofa)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Sus scrofa)
        
        THO complex [nucleoplasm] (Sus scrofa)
        
        THOC5 [nucleoplasm] (Sus scrofa)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Sus scrofa)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Sus scrofa)
        
        THO complex [nucleoplasm] (Sus scrofa)
        
        THOC5 [nucleoplasm] (Sus scrofa)

Metabolism of RNA (Sus scrofa)

- Processing of Capped Intron-Containing Pre-mRNA (Sus scrofa)
  - Transport of Mature Transcript to Cytoplasm (Sus scrofa)
    - Transport of Mature mRNA derived from an Intron-Containing Transcript (Sus scrofa)
      - NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Sus scrofa)
        
        NXF1,2:NXT1::polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Sus scrofa)
        
        capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Sus scrofa)
        
        TREX (minus DDX39B) [nucleoplasm] (Sus scrofa)
        
        THO complex [nucleoplasm] (Sus scrofa)
        
        THOC5 [nucleoplasm] (Sus scrofa)
        
        polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Sus scrofa)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Sus scrofa)
        
        THO complex [nucleoplasm] (Sus scrofa)
        
        THOC5 [nucleoplasm] (Sus scrofa)
  - mRNA 3'-end processing (Sus scrofa)
    - Cleavage of mRNA at the 3'-end (Sus scrofa)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Sus scrofa)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Sus scrofa)
        
        THO complex [nucleoplasm] (Sus scrofa)
        
        THOC5 [nucleoplasm] (Sus scrofa)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Sus scrofa)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Sus scrofa)
        
        THO complex [nucleoplasm] (Sus scrofa)
        
        THOC5 [nucleoplasm] (Sus scrofa)
    - TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally (Sus scrofa)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Sus scrofa)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Sus scrofa)
        
        THO complex [nucleoplasm] (Sus scrofa)
        
        THOC5 [nucleoplasm] (Sus scrofa)
      - THO complex [nucleoplasm] (Sus scrofa)
        
        THOC5 [nucleoplasm] (Sus scrofa)
    - mRNA polyadenylation (Sus scrofa)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Sus scrofa)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Sus scrofa)
        
        THO complex [nucleoplasm] (Sus scrofa)
        
        THOC5 [nucleoplasm] (Sus scrofa)
      - polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Sus scrofa)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Sus scrofa)
        
        THO complex [nucleoplasm] (Sus scrofa)
        
        THOC5 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287AR63

Gene Names

THOC5

Reference Genes

ENSEMBL:ENSSSCG00000009988.5

ENSEMBL:ENSSSCG00005023335.1 THOC5

Other Identifiers

GO:0000346

GO:0000347

GO:0000445

GO:0000781

GO:0005634

GO:0005654

GO:0005694

GO:0006351

GO:0006355

GO:0006406

GO:0006913

GO:0023052

GO:0030154

GO:0030224

GO:0032786

GO:0043226

GO:0046784

GO:0048856

GO:2000002

Ssc.1825.1.A1_at

Ssc.26424.1.S1_at

Participates

as a component of

THO complex [nucleoplasm] (Sus scrofa)

Inferred From

THOC5 [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000100296

Ensembl

ENSSSCP00000046563, ENSSSCG00000009988, ENSSSCT00000041892