Reactome | TF [clathrin-coated endocytic vesicle membrane]

TF [clathrin-coated endocytic vesicle membrane]

Stable Identifier

R-SSC-8869140

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

clathrin-coated endocytic vesicle membrane

Synonyms

apoTF, A0A288CFV5

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Sus scrofa)

- Membrane Trafficking (Sus scrofa)
  - Clathrin-mediated endocytosis (Sus scrofa)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        holoTF:TFRC dimer [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        holoTF [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        TF [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        holoTF:TFRC dimer [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        holoTF [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        TF [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        holoTF:TFRC dimer [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        holoTF [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        TF [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        holoTF:TFRC dimer [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        holoTF [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        TF [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        holoTF:TFRC dimer [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        holoTF [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        TF [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Sus scrofa)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        holoTF:TFRC dimer [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        holoTF [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        TF [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        holoTF:TFRC dimer [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        holoTF [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        TF [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
    - RAB5 and GAPVD1 bind AP-2 (Sus scrofa)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        holoTF:TFRC dimer [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        holoTF [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        TF [clathrin-coated endocytic vesicle membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A288CFV5

Gene Names

Reference Genes

ENSEMBL:ENSSSCG00000011640.5

UCSC:A0A288CFV5 TF

Other Identifiers

396996

GO:0002376

GO:0005576

GO:0005615

GO:0005768

GO:0005769

GO:0005770

GO:0005886

GO:0005905

GO:0006811

GO:0006826

GO:0006879

GO:0007166

GO:0008198

GO:0008199

GO:0009617

GO:0009925

GO:0009986

GO:0016020

GO:0016324

GO:0019731

GO:0019899

GO:0030139

GO:0030154

GO:0030316

GO:0031410

GO:0031982

GO:0032436

GO:0034986

GO:0043226

GO:0044325

GO:0045178

GO:0046872

GO:0048260

GO:0048471

GO:0051241

GO:0055037

GO:0060586

GO:0071281

GO:0098542

GO:0140104

GO:1990459

GO:1990712

Ssc.4222.1.S1_at

Participates

as a component of

holoTF [clathrin-coated endocytic vesicle membrane] (Sus scrofa)

Other forms of this molecule

TF [secretory granule lumen]

phospho-TF [endoplasmic reticulum lumen]

TF [endoplasmic reticulum lumen]

TF [endosome membrane]

TF [extracellular region]

Inferred From

apoTF [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

Cross References

ENSEMBL

ENSSSCT00000012740, ENSSSCP00000012406, ENSSSCG00000011640

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