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MLH1 [nucleoplasm]
Stable Identifier
R-SSC-912495
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
nucleoplasm
Synonyms
MLH1, I3LT92
Locations in the PathwayBrowser
Expand all
DNA Repair (Sus scrofa)
Mismatch Repair (Sus scrofa)
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) (Sus scrofa)
EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch (Sus scrofa)
EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Sus scrofa)
MLH1:PMS2 [nucleoplasm] (Sus scrofa)
MLH1 [nucleoplasm] (Sus scrofa)
EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) (Sus scrofa)
EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Sus scrofa)
MLH1:PMS2 [nucleoplasm] (Sus scrofa)
MLH1 [nucleoplasm] (Sus scrofa)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Sus scrofa)
MLH1:PMS2 [nucleoplasm] (Sus scrofa)
MLH1 [nucleoplasm] (Sus scrofa)
Formation of MSH1:PMS2 Complex (Sus scrofa)
MLH1 [nucleoplasm] (Sus scrofa)
MLH1:PMS2 [nucleoplasm] (Sus scrofa)
MLH1 [nucleoplasm] (Sus scrofa)
MLH1:PMS2 makes single strand incision near 1-2 base mismatch (Sus scrofa)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch [nucleoplasm] (Sus scrofa)
MLH1:PMS2 [nucleoplasm] (Sus scrofa)
MLH1 [nucleoplasm] (Sus scrofa)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Sus scrofa)
MLH1:PMS2 [nucleoplasm] (Sus scrofa)
MLH1 [nucleoplasm] (Sus scrofa)
MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Sus scrofa)
MLH1:PMS2 [nucleoplasm] (Sus scrofa)
MLH1 [nucleoplasm] (Sus scrofa)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch [nucleoplasm] (Sus scrofa)
MLH1:PMS2 [nucleoplasm] (Sus scrofa)
MLH1 [nucleoplasm] (Sus scrofa)
External Reference Information
External Reference
UniProt:I3LT92
Gene Names
MLH1
Reference Genes
ENSEMBL:ENSSSCG00000024222.4
ENSEMBL:ENSSSCG00005036930.1 MLH1
Other Identifiers
100337665
GO:0000228
GO:0000289
GO:0000712
GO:0000793
GO:0000794
GO:0000795
GO:0001673
GO:0002204
GO:0002376
GO:0003677
GO:0003682
GO:0003697
GO:0003824
GO:0005524
GO:0005634
GO:0005654
GO:0005694
GO:0005712
GO:0005715
GO:0005737
GO:0006281
GO:0006298
GO:0006303
GO:0006310
GO:0006974
GO:0007010
GO:0007059
GO:0007060
GO:0007129
GO:0007131
GO:0007140
GO:0007283
GO:0008630
GO:0009617
GO:0012501
GO:0016071
GO:0016321
GO:0016446
GO:0016447
GO:0016787
GO:0016887
GO:0019899
GO:0022414
GO:0023052
GO:0030154
GO:0030983
GO:0032137
GO:0032300
GO:0032389
GO:0032407
GO:0043060
GO:0043226
GO:0043229
GO:0045132
GO:0045141
GO:0045143
GO:0045190
GO:0045950
GO:0048298
GO:0048304
GO:0048477
GO:0048856
GO:0051257
GO:0051321
GO:0140013
GO:0140097
GO:0140299
GO:0140657
GO:0140664
Ssc.3701.1.S1_at
Participates
as an input of
Formation of MSH1:PMS2 Complex (Sus scrofa)
as a component of
MLH1:PMS2 [nucleoplasm] (Sus scrofa)
Inferred From
MLH1 [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000076242
Ensembl
ENSSSCG00000024222
,
ENSSSCP00000027336
,
ENSSSCT00000027443
VGNC
90252
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