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Active ALK dimer [plasma membrane]
Stable Identifier
R-SSC-9700013
Type
Set [DefinedSet]
Species
Sus scrofa
Compartment
plasma membrane
Synonyms
(PTN,MDK):p-7Y ALK dimer
Locations in the PathwayBrowser
Expand all
Signal Transduction (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by ALK (Sus scrofa)
ALK autophosphorylation downstream of PTN and MDK (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
Active ALK binds JAK3 (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
Active ALK:JAK3 [plasma membrane] (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
Active ALK binds PLCG1 (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
Active ALK:PLCG1 [plasma membrane] (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
Active ALK binds SHC1 (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
Active ALK dimer:SHC1 [plasma membrane] (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
Active ALK dimer binds IRS1 (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
Active ALK:IRS1 [plasma membrane] (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
Active ALK phosphorylates IRS1 (Sus scrofa)
Active ALK:IRS1 [plasma membrane] (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
Active ALK:pY-IRS1 [plasma membrane] (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
Active ALK phosphorylates JAK3 (Sus scrofa)
Active ALK:JAK3 [plasma membrane] (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
Active ALK:p-Y980 JAK3 [plasma membrane] (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
Active ALK phosphorylates PLCG1 (Sus scrofa)
Active ALK:PLCG1 [plasma membrane] (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
active ALK:p-4Y PLCG1 [plasma membrane] (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
Active ALK phosphorylates SHC1 (Sus scrofa)
Active ALK dimer:SHC1 [plasma membrane] (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
Active ALK:p-3Y SHC1 [plasma membrane] (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
Active ALK recruits PI3K (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
active ALK:PI3K [plasma membrane] (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
PI3K synthesizes PIP3 downstream of ALK (Sus scrofa)
active ALK:PI3K [plasma membrane] (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
PTPN6 dephosphorylates JAK3 (Sus scrofa)
Active ALK:JAK3 [plasma membrane] (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
Active ALK:p-Y980 JAK3 [plasma membrane] (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
PTPRZ dephosphorylates ligand-bound ALK dimers (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
STAT3 is phosphorylated downstream of active ALK (Sus scrofa)
Active ALK dimer [plasma membrane] (Sus scrofa)
Participants
members
MDK:p-7Y ALK dimer [plasma membrane]
(Sus scrofa)
PTN:p-7Y ALK dimer [plasma membrane]
(Sus scrofa)
Participates
as an input of
PTPRZ dephosphorylates ligand-bound ALK dimers (Sus scrofa)
Active ALK recruits PI3K (Sus scrofa)
Active ALK binds PLCG1 (Sus scrofa)
Active ALK dimer binds IRS1 (Sus scrofa)
Active ALK binds SHC1 (Sus scrofa)
Active ALK binds JAK3 (Sus scrofa)
STAT3 is phosphorylated downstream of active ALK (Sus scrofa)
as a component of
active ALK:PI3K [plasma membrane] (Sus scrofa)
active ALK:p-4Y PLCG1 [plasma membrane] (Sus scrofa)
Active ALK:PLCG1 [plasma membrane] (Sus scrofa)
Active ALK:pY-IRS1 [plasma membrane] (Sus scrofa)
Active ALK:IRS1 [plasma membrane] (Sus scrofa)
Active ALK:p-3Y SHC1 [plasma membrane] (Sus scrofa)
Active ALK dimer:SHC1 [plasma membrane] (Sus scrofa)
Active ALK:JAK3 [plasma membrane] (Sus scrofa)
Active ALK:p-Y980 JAK3 [plasma membrane] (Sus scrofa)
as an output of
ALK autophosphorylation downstream of PTN and MDK (Sus scrofa)
Inferred From
Active ALK dimer [plasma membrane]
(Homo sapiens)
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