Reactome | p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [endosome membrane]

p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [endosome membrane]

Stable Identifier

R-SSC-975171

Type

Complex

Species

Sus scrofa

Compartment

endosome membrane

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

x 3 K63polyUb [cytosol] (Sus scrofa)
p-IRAK2:K63-linked pUb oligo-TRAF6 [endosome membrane] (Sus scrofa)
x 3 phospho-p-T184,T187-MAP3K7 [endosome membrane] (Sus scrofa)
x 3 TAB1 [endosome membrane] (Sus scrofa)
x 3 TAB2/3 [endosome membrane] (Sus scrofa)

Participates

as an output of

Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Sus scrofa)

Inferred From

p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [endosome membrane] (Homo sapiens)

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