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Wnt11 binds Fzd7 to regulate convergent extension in Xenopus
Stable Identifier
R-XLA-4568832
Type
Reaction [binding]
Species
Xenopus laevis
Compartment
plasma membrane
,
extracellular region
ReviewStatus
5/5
General
SBML
|
BioPAX
Level 2
Level 3
|
PDF
SVG
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SBGN
Direct binding between XWnt11 and XFzd7 has been demonstrated by co-immunoprecipitation in Xenopus embryos. In this system, Wnt11 and Fzd7 contribute to convergent extension during gastrulation (Djiane et al, 2000).
Literature References
PubMed ID
Title
Journal
Year
10862746
Role of frizzled 7 in the regulation of convergent extension movements during gastrulation in Xenopus laevis
Shi, D
,
Riou, J
,
Djiane, A
,
Umbhauer, M
,
Boucaut, JC
Development
2000
Participants
Input
Fzd7a [plasma membrane]
(Xenopus laevis)
Wnt11 [extracellular region]
(Xenopus laevis)
Output
Wnt11:Fzd7a [plasma membrane]
(Xenopus laevis)
Orthologous Events
WNTs bind the FZD receptor to initiate PCP pathway (Homo sapiens)
Authored
Rothfels, K (2013-09-14)
Reviewed
Kikuchi, A (2013-11-13)
Created
Rothfels, K (2013-09-19)
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