Reactome | tgfb2 [extracellular region]

tgfb2 [extracellular region]

Stable Identifier

R-XTR-114706

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

extracellular region

Synonyms

TGFB2, A0A6I8R415

Locations in the PathwayBrowser

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Extracellular matrix organization (Xenopus tropicalis)

- Elastic fibre formation (Xenopus tropicalis)
  - Molecules associated with elastic fibres (Xenopus tropicalis)
    - LTBP1, LTBP3 bind TGF-Beta (Xenopus tropicalis)
      - LTBP1,LTBP3:TGFB:LAP [extracellular region] (Xenopus tropicalis)
        
        LTBP1,LTBP3:TGFB2:LAP2 [extracellular region] (Xenopus tropicalis)
        
        TGFB2:LAP2 [extracellular region] (Xenopus tropicalis)
        
        tgfb2 [extracellular region] (Xenopus tropicalis)
      - TGFB:LAP [extracellular region] (Xenopus tropicalis)
        
        TGFB2:LAP2 [extracellular region] (Xenopus tropicalis)
        
        tgfb2 [extracellular region] (Xenopus tropicalis)

Hemostasis (Xenopus tropicalis)

- Platelet activation, signaling and aggregation (Xenopus tropicalis)
  - Response to elevated platelet cytosolic Ca2+ (Xenopus tropicalis)
    - Platelet degranulation (Xenopus tropicalis)
      - Exocytosis of platelet alpha granule contents (Xenopus tropicalis)
        
        Platelet alpha granule contents [extracellular region] (Xenopus tropicalis)
        
        TGF beta [extracellular region] (Xenopus tropicalis)
        
        tgfb2 [extracellular region] (Xenopus tropicalis)

Signal Transduction (Xenopus tropicalis)

- Signaling by TGFB family members (Xenopus tropicalis)
  - Signaling by TGF-beta Receptor Complex (Xenopus tropicalis)
    - TGF-beta receptor signaling activates SMADs (Xenopus tropicalis)
      - LTBP1, LTBP3 bind TGF-Beta (Xenopus tropicalis)
        
        LTBP1,LTBP3:TGFB:LAP [extracellular region] (Xenopus tropicalis)
        
        LTBP1,LTBP3:TGFB2:LAP2 [extracellular region] (Xenopus tropicalis)
        
        TGFB2:LAP2 [extracellular region] (Xenopus tropicalis)
        
        tgfb2 [extracellular region] (Xenopus tropicalis)
        
        TGFB:LAP [extracellular region] (Xenopus tropicalis)
        
        TGFB2:LAP2 [extracellular region] (Xenopus tropicalis)
        
        tgfb2 [extracellular region] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A0A6I8R415

Gene Names

tgfb2

Reference Genes

BioGPS Gene:100489680 tgfb2

ENSEMBL:ENSXETG00000015347

KEGG Gene (Xenopus tropicalis):100489680 tgfb2

Monarch:100489680 tgfb2

NCBI Gene:100489680 tgfb2

Reference Transcript

RefSeq:XM_002936021.5 tgfb2

Other Identifiers

100489680

GO:0005160

GO:0005576

GO:0005615

GO:0007165

GO:0008083

GO:0009790

GO:0009888

GO:0023052

GO:0042221

GO:0048018

GO:0048856

GO:0051781

GO:0098772

Participates

as a member of

TGF beta [extracellular region] (Xenopus tropicalis)

as a component of

TGFB2:LAP2 [extracellular region] (Xenopus tropicalis)

Other forms of this molecule

tgfb2 [platelet alpha granule lumen]

tgfb2 [extracellular region]

Inferred From

TGFB2 [extracellular region] (Homo sapiens)

Cross References

RefSeq

XP_002936067.1

Ensembl

ENSXETG00000015347, ENSXETT00000086866, ENSXETP00000079458

Xenbase

XB-GENE-480560

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