Reactome | BTRC:CUL1:SKP1 [cytosol]

BTRC:CUL1:SKP1 [cytosol]

Stable Identifier

R-XTR-174155

Type

Complex

Species

Xenopus tropicalis

Compartment

cytosol

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

btrc [cytosol] (Xenopus tropicalis)
cul1 [cytosol] (Xenopus tropicalis)
skp1 [cytosol] (Xenopus tropicalis)

Participates

as an output of

SCF-beta-TrCP ubiquitinylates IkB (Xenopus tropicalis)
SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA (Xenopus tropicalis)
SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 (Xenopus tropicalis)
SCF-mediated degradation of Emi1 (Xenopus tropicalis)

as an input of

SCF with beta-TrCP1 or beta-TrCP2 binds NF-kappaB:phospho-IkB (Xenopus tropicalis)
SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB (Xenopus tropicalis)
Phosphorylated BORA binds SCF-beta-TrCp1/2 (Xenopus tropicalis)
SCF betaTrCP1,2 binds p-NFkB p105:TPL2:ABIN2 (Xenopus tropicalis)
Phosphorylated Emi1 binds the beta-TrCP in the SCF complex (Xenopus tropicalis)

as a component of

NF-kappaB:p-IkB:SCF-betaTrCP [cytosol] (Xenopus tropicalis)
p-S252,S497,T501-BORA:SCF-beta-TrCp1/2 [cytosol] (Xenopus tropicalis)
Active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP [cytosol] (Xenopus tropicalis)
SCF-beta-TrCP1,2:p-S927,S932-NFKB1:p-S,T-MAP3K8:TNIP2 [cytosol] (Xenopus tropicalis)
SCF-beta-TrCP:phospho-Emi1 complexes [cytosol] (Xenopus tropicalis)

Inferred From

SCF-beta-TRCP [cytosol] (Homo sapiens)

(BTRC:CUL1:SKP1),(FBXW11:CUL1:SKP1) [cytosol] (Homo sapiens)

BTRC:CUL1:SKP1 [cytosol] (Homo sapiens)