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frs2 [cytosol]
Stable Identifier
R-XTR-190244
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
FRS2, B5DE89
Locations in the PathwayBrowser
Expand all
Signal Transduction (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by NTRKs (Xenopus tropicalis)
Signaling by NTRK1 (TRKA) (Xenopus tropicalis)
Signalling to ERKs (Xenopus tropicalis)
Prolonged ERK activation events (Xenopus tropicalis)
Frs2-mediated activation (Xenopus tropicalis)
FRS2 binds to active TrkA receptor (Xenopus tropicalis)
Active TrkA receptor:FRS2 complex [endosome membrane] (Xenopus tropicalis)
frs2 [cytosol] (Xenopus tropicalis)
frs2 [cytosol] (Xenopus tropicalis)
FRS2 is phosphorylated by active TrkA receptor (Xenopus tropicalis)
Active TrkA receptor:FRS2 complex [endosome membrane] (Xenopus tropicalis)
frs2 [cytosol] (Xenopus tropicalis)
Signaling by NTRK2 (TRKB) (Xenopus tropicalis)
Activated NTRK2 signals through FRS2 and FRS3 (Xenopus tropicalis)
Activated NTRK2 binds FRS2 (Xenopus tropicalis)
BDNF,NTF4:p-5Y-NTRK2:FRS2 [plasma membrane] (Xenopus tropicalis)
frs2 [cytosol] (Xenopus tropicalis)
frs2 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:B5DE89
Gene Names
frs2
Reference Genes
BioGPS Gene:100038035 frs2
ENSEMBL:ENSXETG00000001426
KEGG:xtr:100038035 frs2
Monarch:100038035 frs2
NCBI Gene:100038035 frs2
UCSC:B5DE89 frs2
Reference Transcript
RefSeq:XM_012958358.3 frs2
RefSeq:NM_001134809.1 frs2
Other Identifiers
100038035
GO:0005068
GO:0005104
GO:0005737
GO:0005886
GO:0005911
GO:0008543
GO:0016020
GO:0060090
Participates
as an input of
Activated NTRK2 binds FRS2 (Xenopus tropicalis)
FRS2 binds to active TrkA receptor (Xenopus tropicalis)
as a component of
BDNF,NTF4:p-5Y-NTRK2:FRS2 [plasma membrane] (Xenopus tropicalis)
Active TrkA receptor:FRS2 complex [endosome membrane] (Xenopus tropicalis)
Other forms of this molecule
phospho-frs2 [cytosol]
phospho-frs2 [cytosol]
phospho-frs2 [plasma membrane]
frs2 [plasma membrane]
phospho-frs2 [plasma membrane]
Inferred From
FRS2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_012813812.1
,
NP_001128281.1
ENSEMBL
ENSXETT00000003016
,
ENSXETG00000001426
,
ENSXETP00000003016
Xenbase
XB-GENE-479760
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