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plcg1 [cytosol]
Stable Identifier
R-XTR-202320
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
PLCG1, F6Z8A1
Locations in the PathwayBrowser
Expand all
Immune System (Xenopus tropicalis)
Adaptive Immune System (Xenopus tropicalis)
TCR signaling (Xenopus tropicalis)
Generation of second messenger molecules (Xenopus tropicalis)
Phosphorylation of PLC-gamma1 (Xenopus tropicalis)
PLCG1:p-3Y-SLP-76:Gads:LAT [plasma membrane] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
Innate Immune System (Xenopus tropicalis)
DAP12 interactions (Xenopus tropicalis)
DAP12 signaling (Xenopus tropicalis)
Activation of RAC1 by VAV2/3 (Xenopus tropicalis)
p-5Y-LAT:PLCG1:GADS:p-3Y-SLP-76:BTK:p-VAV [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS1:GADS:p-3Y-SLP-76:PLCG:VAV:p-Y223,Y551-BTK [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
Recruitment of PLC-gamma to SLP-76 and p-5Y-LAT (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76:PLCG [plasma membrane] (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
Recruitment of VAV and BTK to p-SLP-76 (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG:VAV:BTK:PIP3 [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
Fc epsilon receptor (FCERI) signaling (Xenopus tropicalis)
FCERI mediated Ca+2 mobilization (Xenopus tropicalis)
Autophosphorylation of BTK/ITK (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-TEC kinases [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
FCERI mediated MAPK activation (Xenopus tropicalis)
Activation of RAC1 by VAV (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
Autophosphorylation of PAK (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
Phosphorylation and activation of VAV (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
Recruitment of PAK to the membrane by binding active RAC1 (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
Recruitment of PLC-gamma to SLP-76 and p-5Y-LAT (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76:PLCG [plasma membrane] (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
Recruitment of VAV to p-SLP-76 (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] (Xenopus tropicalis)
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by EGFR (Xenopus tropicalis)
EGFR interacts with phospholipase C-gamma (Xenopus tropicalis)
EGFR activates PLC-gamma1 by phosphorylation (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
Phospholipase C-gamma1 binds to the activated EGF receptor (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
Signaling by VEGF (Xenopus tropicalis)
VEGFA-VEGFR2 Pathway (Xenopus tropicalis)
VEGFR2 mediated cell proliferation (Xenopus tropicalis)
p-6Y-VEGFR2 binds PLCG1 (Xenopus tropicalis)
VEGFA dimer:p-6Y-VEGFR2 dimer:PLCG1 [plasma membrane] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
plcg1 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:F6Z8A1
Gene Names
plcg1
Reference Genes
ENSEMBL:ENSXETG00000019423
KEGG Gene (Xenopus tropicalis):100496674 plcg1
Reference Transcript
RefSeq:XM_018097895.2 plcg1
RefSeq:XM_012952768.3 plcg1
RefSeq:XM_018097896.2 plcg1
Other Identifiers
100496674
GO:0003824
GO:0004435
GO:0005509
GO:0006629
GO:0007165
GO:0008081
GO:0009395
GO:0016042
GO:0016787
GO:0023052
GO:0035556
GO:0046872
GO:0050896
Participates
as a component of
PLCG1:p-3Y-SLP-76:Gads:LAT [plasma membrane] (Xenopus tropicalis)
VEGFA dimer:p-6Y-VEGFR2 dimer:PLCG1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane] (Xenopus tropicalis)
as an input of
p-6Y-VEGFR2 binds PLCG1 (Xenopus tropicalis)
Phospholipase C-gamma1 binds to the activated EGF receptor (Xenopus tropicalis)
as a member of
PLC gamma1,2 [cytosol] (Xenopus tropicalis)
Other forms of this molecule
phospho-plcg1 [cytosol]
plcg1 [plasma membrane]
phospho-plcg1 [plasma membrane]
Inferred From
PLCG1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_017953385.2
,
XP_017953384.2
,
XP_012808222.3
Ensembl
ENSXETG00000019423
,
ENSXETP00000091697
,
ENSXETT00000068525
,
ENSXETT00000042118
,
ENSXETP00000042118
Xenbase
XB-GENE-982496
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