Reactome | cdk8 [nucleoplasm]

cdk8 [nucleoplasm]

Stable Identifier

R-XTR-212440

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

nucleoplasm

Synonyms

CDK8, Q6P3N6

Locations in the PathwayBrowser

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Gene expression (Transcription) (Xenopus tropicalis)

- RNA Polymerase II Transcription (Xenopus tropicalis)
  - Generic Transcription Pathway (Xenopus tropicalis)
    - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Xenopus tropicalis)
      - SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Xenopus tropicalis)
        
        Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Xenopus tropicalis)
        
        CDK8:CCNC/ CDK9:CCNT [nucleoplasm] (Xenopus tropicalis)
        
        CDK8:CCNC [nucleoplasm] (Xenopus tropicalis)
        
        cdk8 [nucleoplasm] (Xenopus tropicalis)

Signal Transduction (Xenopus tropicalis)

- Signaling by TGFB family members (Xenopus tropicalis)
  - Signaling by TGF-beta Receptor Complex (Xenopus tropicalis)
    - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Xenopus tropicalis)
      - SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Xenopus tropicalis)
        
        Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Xenopus tropicalis)
        
        CDK8:CCNC/ CDK9:CCNT [nucleoplasm] (Xenopus tropicalis)
        
        CDK8:CCNC [nucleoplasm] (Xenopus tropicalis)
        
        cdk8 [nucleoplasm] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:Q6P3N6

Gene Names

cdk8

Reference Genes

BioGPS Gene:394856 cdk8

ENSEMBL:ENSXETG00000009787

KEGG Gene (Xenopus tropicalis):394856 cdk8

Monarch:394856 cdk8

NCBI Gene:394856 cdk8

Reference Transcript

RefSeq:NM_203915.1 cdk8

Participates

as a component of

CDK8:CCNC [nucleoplasm] (Xenopus tropicalis)

Inferred From

CDK8 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_989246.1

Xenbase

XB-GENE-962267

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