Reactome | smc1a [chromosome, centromeric region]

smc1a [chromosome, centromeric region]

Stable Identifier

R-XTR-2466015

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

chromosome, centromeric region

Synonyms

SMC1A, A0A6I8QZH2

Locations in the PathwayBrowser

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Cell Cycle (Xenopus tropicalis)

- Cell Cycle, Mitotic (Xenopus tropicalis)
  - M Phase (Xenopus tropicalis)
    - Mitotic Metaphase and Anaphase (Xenopus tropicalis)
      - Mitotic Anaphase (Xenopus tropicalis)
        
        Separation of Sister Chromatids (Xenopus tropicalis)
        
        ESPL1 (Separase) cleaves centromeric cohesin (Xenopus tropicalis)
        
        Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Xenopus tropicalis)
        
        Cleaved Cohesin [chromosome, centromeric region] (Xenopus tropicalis)
        
        smc1a [chromosome, centromeric region] (Xenopus tropicalis)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Xenopus tropicalis)
        
        p-RAD21-Ac-Cohesin [chromosome, centromeric region] (Xenopus tropicalis)
        
        smc1a [chromosome, centromeric region] (Xenopus tropicalis)
    - Mitotic Prometaphase (Xenopus tropicalis)
      - Resolution of Sister Chromatid Cohesion (Xenopus tropicalis)
        
        CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Xenopus tropicalis)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Xenopus tropicalis)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Xenopus tropicalis)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Xenopus tropicalis)
        
        Ac-Cohesin Complex [chromosome, centromeric region] (Xenopus tropicalis)
        
        smc1a [chromosome, centromeric region] (Xenopus tropicalis)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Xenopus tropicalis)
        
        Ac-Cohesin Complex [chromosome, centromeric region] (Xenopus tropicalis)
        
        smc1a [chromosome, centromeric region] (Xenopus tropicalis)
        
        Kinetochore assembly (Xenopus tropicalis)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Xenopus tropicalis)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Xenopus tropicalis)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Xenopus tropicalis)
        
        Ac-Cohesin Complex [chromosome, centromeric region] (Xenopus tropicalis)
        
        smc1a [chromosome, centromeric region] (Xenopus tropicalis)
        
        Sister Centromeres:Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Xenopus tropicalis)
        
        Centromere:Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Xenopus tropicalis)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region] (Xenopus tropicalis)
        
        Ac-Cohesin Complex [chromosome, centromeric region] (Xenopus tropicalis)
        
        smc1a [chromosome, centromeric region] (Xenopus tropicalis)
        
        PP2A-B56 dephosphorylates centromeric cohesin (Xenopus tropicalis)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Xenopus tropicalis)
        
        p-RAD21-Ac-Cohesin [chromosome, centromeric region] (Xenopus tropicalis)
        
        smc1a [chromosome, centromeric region] (Xenopus tropicalis)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Xenopus tropicalis)
        
        p-STAG2,RAD21-Ac-Cohesin [chromosome, centromeric region] (Xenopus tropicalis)
        
        smc1a [chromosome, centromeric region] (Xenopus tropicalis)
        
        Phosphorylation of cohesin by PLK1 at centromeres (Xenopus tropicalis)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Xenopus tropicalis)
        
        Ac-Cohesin Complex [chromosome, centromeric region] (Xenopus tropicalis)
        
        smc1a [chromosome, centromeric region] (Xenopus tropicalis)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Xenopus tropicalis)
        
        p-STAG2,RAD21-Ac-Cohesin [chromosome, centromeric region] (Xenopus tropicalis)
        
        smc1a [chromosome, centromeric region] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A0A6I8QZH2

Gene Names

smc1a

Reference Genes

BioGPS Gene:100493711 smc1a

ENSEMBL:ENSXETG00000024747

KEGG:xtr:100493711 smc1a

Monarch:100493711 smc1a

NCBI Gene:100493711 smc1a

UCSC:A0A6I8QZH2 smc1a

Reference Transcript

RefSeq:XM_002935514.4 smc1a

Other Identifiers

100493711

GO:0003824

GO:0005524

GO:0005634

GO:0005694

GO:0007049

GO:0007062

GO:0008278

GO:0016787

GO:0016887

GO:0043226

GO:0051276

GO:0140657

Participates

as a component of

Other forms of this molecule

smc1a [chromosome]

smc1a [nucleoplasm]

Inferred From

SMC1A [chromosome, centromeric region] (Homo sapiens)

Cross References

RefSeq

XP_002935560.1

ENSEMBL

ENSXETP00000074499, ENSXETT00000088439, ENSXETG00000024747

Xenbase

XB-GENE-972620