Reactome | MGC107780 [extracellular region]

MGC107780 [extracellular region]

Stable Identifier

R-XTR-2530438

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

extracellular region

Synonyms

FCN2, Q5FWS0

Locations in the PathwayBrowser

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Immune System (Xenopus tropicalis)

- Innate Immune System (Xenopus tropicalis)
  - Complement cascade (Xenopus tropicalis)
    - Initial triggering of complement (Xenopus tropicalis)
      - Conversion of C2 into C2a and C2b (Xenopus tropicalis)
        
        MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Xenopus tropicalis)
        
        Ficolin-2:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Xenopus tropicalis)
        
        FCN2 dodecamer [extracellular region] (Xenopus tropicalis)
        
        FCN2 trimer [extracellular region] (Xenopus tropicalis)
        
        MGC107780 [extracellular region] (Xenopus tropicalis)
      - Conversion of C4 into C4a and C4b (Xenopus tropicalis)
        
        MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Xenopus tropicalis)
        
        Ficolin-2:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Xenopus tropicalis)
        
        FCN2 dodecamer [extracellular region] (Xenopus tropicalis)
        
        FCN2 trimer [extracellular region] (Xenopus tropicalis)
        
        MGC107780 [extracellular region] (Xenopus tropicalis)
      - Creation of C4 and C2 activators (Xenopus tropicalis)
        
        Lectin pathway of complement activation (Xenopus tropicalis)
        
        Activation of MASPs (Xenopus tropicalis)
        
        MBL2,FCN:MASPs:carbohydrate patterns [plasma membrane] (Xenopus tropicalis)
        
        FCN2 ligands:FCN2 dodecamer:MASP1 dimer:MASP2-1 dimer:4xCa2+ [plasma membrane] (Xenopus tropicalis)
        
        FCN2 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Xenopus tropicalis)
        
        FCN2 dodecamer [extracellular region] (Xenopus tropicalis)
        
        FCN2 trimer [extracellular region] (Xenopus tropicalis)
        
        MGC107780 [extracellular region] (Xenopus tropicalis)
        
        MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Xenopus tropicalis)
        
        Ficolin-2:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Xenopus tropicalis)
        
        FCN2 dodecamer [extracellular region] (Xenopus tropicalis)
        
        FCN2 trimer [extracellular region] (Xenopus tropicalis)
        
        MGC107780 [extracellular region] (Xenopus tropicalis)
        
        Ficolins bind to repetitive carbohydrate structures on the target cell surface (Xenopus tropicalis)
        
        Ficolin-2 binds to molecular patterns on the target cell surface (Xenopus tropicalis)
        
        FCN2 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Xenopus tropicalis)
        
        FCN2 dodecamer [extracellular region] (Xenopus tropicalis)
        
        FCN2 trimer [extracellular region] (Xenopus tropicalis)
        
        MGC107780 [extracellular region] (Xenopus tropicalis)
        
        FCN2 ligands:FCN2 dodecamer:MASP1 dimer:MASP2-1 dimer:4xCa2+ [plasma membrane] (Xenopus tropicalis)
        
        FCN2 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Xenopus tropicalis)
        
        FCN2 dodecamer [extracellular region] (Xenopus tropicalis)
        
        FCN2 trimer [extracellular region] (Xenopus tropicalis)
        
        MGC107780 [extracellular region] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:Q5FWS0

Gene Names

MGC107780

Reference Genes

BioGPS Gene:548409 MGC107780

ENSEMBL:ENSXETG00000008638

KEGG Gene (Xenopus tropicalis):548409 MGC107780

Monarch:548409 MGC107780

NCBI Gene:548409 MGC107780

Reference Transcript

RefSeq:NM_001015692.1 MGC107780

Other Identifiers

100496945

548409

Participates

as a component of

FCN2 trimer [extracellular region] (Xenopus tropicalis)

Other forms of this molecule

MGC107780 [secretory granule lumen]

MGC107780 [ficolin-1-rich granule lumen]

MGC107780 [extracellular region]

Inferred From

FCN2 [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_001015692.1

Ensembl

ENSXETP00000018893, ENSXETT00000018893, ENSXETG00000008638

Xenbase

XB-GENE-29099131