Reactome | ube2i [nucleoplasm]

ube2i [nucleoplasm]

Stable Identifier

R-XTR-3730617

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

nucleoplasm

Synonyms

SUMO1-C93-UBE2I, Q28CQ4

Locations in the PathwayBrowser

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DNA Repair (Xenopus tropicalis)

- DNA Double-Strand Break Repair (Xenopus tropicalis)
  - DNA Double Strand Break Response (Xenopus tropicalis)
    - Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Xenopus tropicalis)
      - PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs (Xenopus tropicalis)
        
        SUMO1:C93-UBE2I [nucleoplasm] (Xenopus tropicalis)
        
        ube2i [nucleoplasm] (Xenopus tropicalis)
- Nucleotide Excision Repair (Xenopus tropicalis)
  - Global Genome Nucleotide Excision Repair (GG-NER) (Xenopus tropicalis)
    - Formation of Incision Complex in GG-NER (Xenopus tropicalis)
      - SUMOylation of XPC (Xenopus tropicalis)
        
        SUMO1,2,3:UBE2I [nucleoplasm] (Xenopus tropicalis)
        
        SUMO1:C93-UBE2I [nucleoplasm] (Xenopus tropicalis)
        
        ube2i [nucleoplasm] (Xenopus tropicalis)

Gene expression (Transcription) (Xenopus tropicalis)

- RNA Polymerase II Transcription (Xenopus tropicalis)
  - Generic Transcription Pathway (Xenopus tropicalis)
    - Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Xenopus tropicalis)
      - Negative regulation of activity of TFAP2 (AP-2) family transcription factors (Xenopus tropicalis)
        
        SUMOylation of TFAP2C with SUMO1 (Xenopus tropicalis)
        
        SUMO1:C93-UBE2I [nucleoplasm] (Xenopus tropicalis)
        
        ube2i [nucleoplasm] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:Q28CQ4

Gene Names

ube2i

Reference Genes

BioGPS Gene:549162 ube2i

ENSEMBL:ENSXETG00000004027

KEGG Gene (Xenopus tropicalis):549162 ube2i

Monarch:549162 ube2i

NCBI Gene:549162 ube2i

Reference Transcript

Other Identifiers

549162

GO:0000166

GO:0003824

GO:0004674

GO:0005524

GO:0005634

GO:0005737

GO:0006468

GO:0007049

GO:0007059

GO:0007216

GO:0014069

GO:0016740

GO:0016925

GO:0023052

GO:0035256

GO:0036211

GO:0043226

GO:0045202

GO:0051301

GO:0140096

Participates

as a component of

SUMO1:C93-UBE2I [nucleoplasm] (Xenopus tropicalis)

Other forms of this molecule

ube2i [nucleoplasm]

ube2i [nuclear envelope]

ube2i [nucleoplasm]

ube2i [cytosol]

ube2i [nucleoplasm]

Inferred From

SUMO1-C93-UBE2I [nucleoplasm] (Homo sapiens)

Modified Residues

Name

Inter-chain Crosslink via S-(glycyl)-L-cysteine (Cys-Gly) at 93 and 97 (in Homo sapiens)

Coordinate

PsiMod Name

S-(glycyl)-L-cysteine (Cys-Gly)

PsiMod Definition

A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a thioester bond to form S-glycyl-L-cysteine.

Cross References

RefSeq

XP_012825872.1, XP_012825871.1, NP_001016408.1, XP_012825873.1

Xenbase

XB-GENE-974017

Ensembl

ENSXETT00000054232, ENSXETP00000054232, ENSXETG00000004027

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