Reactome | spsb3 [cytosol]

spsb3 [cytosol]

Stable Identifier

R-XTR-400242

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

SPSB3, Q28DT9

Locations in the PathwayBrowser

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Metabolism of proteins (Xenopus tropicalis)

- Post-translational protein modification (Xenopus tropicalis)
  - Neddylation (Xenopus tropicalis)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Xenopus tropicalis)
        
        CRL E3 ubiquitin ligases [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        CUL5-box protein [cytosol] (Xenopus tropicalis)
        
        spsb3 [cytosol] (Xenopus tropicalis)
      - CRL E3 ubiquitin ligases [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        CUL5-box protein [cytosol] (Xenopus tropicalis)
        
        spsb3 [cytosol] (Xenopus tropicalis)
    - COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Xenopus tropicalis)
        
        CRL E3 ubiquitin ligases [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        CUL5-box protein [cytosol] (Xenopus tropicalis)
        
        spsb3 [cytosol] (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        CUL5-box protein [cytosol] (Xenopus tropicalis)
        
        spsb3 [cytosol] (Xenopus tropicalis)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        CUL5-box protein [cytosol] (Xenopus tropicalis)
        
        spsb3 [cytosol] (Xenopus tropicalis)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        NEDD8-CRL5 E3 ligase [cytosol] (Xenopus tropicalis)
        
        CUL5-box protein [cytosol] (Xenopus tropicalis)
        
        spsb3 [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:Q28DT9

Gene Names

spsb3

Reference Genes

BioGPS Gene:550104 spsb3

ENSEMBL:ENSXETG00000010355

KEGG Gene (Xenopus tropicalis):550104 spsb3

Monarch:550104 spsb3

NCBI Gene:550104 spsb3

Reference Transcript

Other Identifiers

550104

GO:0005515

GO:0016567

GO:0036211

Participates

as a member of

CUL5-box protein [cytosol] (Xenopus tropicalis)

Inferred From

SPSB3 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_012825936.1, XP_012825938.1, XP_012825937.1, XP_017952622.1, NP_001017350.1

Xenbase

XB-GENE-971062

Ensembl

ENSXETT00000022767, ENSXETG00000010355, ENSXETP00000022767

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