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About
What is Reactome ?
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Team
Scientific Advisory Board
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Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
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Docs
Userguide
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How do I search ?
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K63polyUb [cytosol]
Stable Identifier
R-XTR-450152
Type
Polymer
Species
Xenopus tropicalis
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Xenopus tropicalis)
Cytokine Signaling in Immune system (Xenopus tropicalis)
Signaling by Interleukins (Xenopus tropicalis)
Interleukin-17 signaling (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
TNFR2 non-canonical NF-kB pathway (Xenopus tropicalis)
TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
Innate Immune System (Xenopus tropicalis)
Alpha-protein kinase 1 signaling pathway (Xenopus tropicalis)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Xenopus tropicalis)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Xenopus tropicalis)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:p-T184,T187-TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Xenopus tropicalis)
NOD1/2 Signaling Pathway (Xenopus tropicalis)
RIP2 is K63 polyubiquitinated (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
Toll-like Receptor Cascades (Xenopus tropicalis)
Toll Like Receptor 10 (TLR10) Cascade (Xenopus tropicalis)
MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
IRAK2 mediated activation of TAK1 complex (Xenopus tropicalis)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [plasma membrane] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
Toll Like Receptor 2 (TLR2) Cascade (Xenopus tropicalis)
Toll Like Receptor TLR1:TLR2 Cascade (Xenopus tropicalis)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
IRAK2 mediated activation of TAK1 complex (Xenopus tropicalis)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [plasma membrane] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
Toll Like Receptor TLR6:TLR2 Cascade (Xenopus tropicalis)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
IRAK2 mediated activation of TAK1 complex (Xenopus tropicalis)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [plasma membrane] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
Toll Like Receptor 3 (TLR3) Cascade (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
Toll Like Receptor 4 (TLR4) Cascade (Xenopus tropicalis)
MyD88-independent TLR4 cascade (Xenopus tropicalis)
TRIF (TICAM1)-mediated TLR4 signaling (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
IRAK2 mediated activation of TAK1 complex (Xenopus tropicalis)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [plasma membrane] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
Toll Like Receptor 5 (TLR5) Cascade (Xenopus tropicalis)
MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
IRAK2 mediated activation of TAK1 complex (Xenopus tropicalis)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [plasma membrane] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Xenopus tropicalis)
MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Xenopus tropicalis)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [endosome membrane] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [endosome membrane] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
Toll Like Receptor 9 (TLR9) Cascade (Xenopus tropicalis)
MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Xenopus tropicalis)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [endosome membrane] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [endosome membrane] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
Activated TAK complexes [cytosol] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
Metabolism of proteins (Xenopus tropicalis)
Post-translational protein modification (Xenopus tropicalis)
Deubiquitination (Xenopus tropicalis)
Josephin domain DUBs (Xenopus tropicalis)
ATXN3 family cleave Ub chains (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
Metalloprotease DUBs (Xenopus tropicalis)
BRISC complex deubiquitinates NLRP3 (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
PSMD14 cleaves K63-linked ubiquitin (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
STAMBPL1 is a deubiquitinase (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
Ovarian tumor domain proteases (Xenopus tropicalis)
TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
Ub-specific processing proteases (Xenopus tropicalis)
USP10 deubiquitinates SNX3, CFTR (Xenopus tropicalis)
PolyUb [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Xenopus tropicalis)
PolyUb [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
USP18 deubiquitinates TAK1:TAB1 (Xenopus tropicalis)
PolyUb [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
USP20, USP33 deubiquitinate ADRB2 (Xenopus tropicalis)
PolyUb [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
USP21 deubiquitinates RIPK1,DDX58 (Xenopus tropicalis)
PolyUb [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
USP25 deubiquitinates DDX58 (Xenopus tropicalis)
PolyUb [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
USP33 deubiquitinates CCP110,ARRB (Xenopus tropicalis)
PolyUb [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
USP4 deubiquitinate TRAF2,TRAF6 (Xenopus tropicalis)
PolyUb [cytosol] (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
Death Receptor Signaling (Xenopus tropicalis)
TNF signaling (Xenopus tropicalis)
TNFR1-induced NF-kappa-B signaling pathway (Xenopus tropicalis)
BIRC(cIAP1/2) ubiquitinates RIPK1 (Xenopus tropicalis)
K63polyUb [cytosol] (Xenopus tropicalis)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
repeated unit
K63-Ub [cytosol]
(Xenopus tropicalis)
Participates
as an output of
TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Xenopus tropicalis)
BRISC complex deubiquitinates NLRP3 (Xenopus tropicalis)
ATXN3 family cleave Ub chains (Xenopus tropicalis)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation (Xenopus tropicalis)
as an input of
STAMBPL1 is a deubiquitinase (Xenopus tropicalis)
PSMD14 cleaves K63-linked ubiquitin (Xenopus tropicalis)
ATXN3 family cleave Ub chains (Xenopus tropicalis)
TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK (Xenopus tropicalis)
BIRC(cIAP1/2) ubiquitinates RIPK1 (Xenopus tropicalis)
RIP2 is K63 polyubiquitinated (Xenopus tropicalis)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Xenopus tropicalis)
as a component of
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [endosome membrane] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [endosome membrane] (Xenopus tropicalis)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:p-T184,T187-TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Xenopus tropicalis)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [plasma membrane] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Xenopus tropicalis)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Xenopus tropicalis)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Xenopus tropicalis)
as a member of
PolyUb [cytosol] (Xenopus tropicalis)
Inferred From
Short K63polyUb [cytosol]
(Homo sapiens)
K63polyUb [cytosol]
(Homo sapiens)
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