Reactome | xrcc2 [nucleoplasm]

xrcc2 [nucleoplasm]

Stable Identifier

R-XTR-5685302

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

nucleoplasm

Synonyms

XRCC2, A0A803K192

Locations in the PathwayBrowser

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DNA Repair (Xenopus tropicalis)

- DNA Double-Strand Break Repair (Xenopus tropicalis)
  - Homology Directed Repair (Xenopus tropicalis)
    - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Xenopus tropicalis)
      - HDR through Homologous Recombination (HRR) (Xenopus tropicalis)
        
        Resolution of D-Loop Structures (Xenopus tropicalis)
        
        Resolution of D-loop Structures through Holliday Junction Intermediates (Xenopus tropicalis)
        
        Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Xenopus tropicalis)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Xenopus tropicalis)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Xenopus tropicalis)
        
        BCDX2 complex [nucleoplasm] (Xenopus tropicalis)
        
        xrcc2 [nucleoplasm] (Xenopus tropicalis)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Xenopus tropicalis)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Xenopus tropicalis)
        
        BCDX2 complex [nucleoplasm] (Xenopus tropicalis)
        
        xrcc2 [nucleoplasm] (Xenopus tropicalis)
        
        Ligation of DNA and formation of Holliday structures following repair synthesis (Xenopus tropicalis)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Xenopus tropicalis)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Xenopus tropicalis)
        
        BCDX2 complex [nucleoplasm] (Xenopus tropicalis)
        
        xrcc2 [nucleoplasm] (Xenopus tropicalis)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Xenopus tropicalis)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Xenopus tropicalis)
        
        BCDX2 complex [nucleoplasm] (Xenopus tropicalis)
        
        xrcc2 [nucleoplasm] (Xenopus tropicalis)
        
        MUS81:EME1,EME2 cleaves D-loop (Xenopus tropicalis)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Xenopus tropicalis)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Xenopus tropicalis)
        
        BCDX2 complex [nucleoplasm] (Xenopus tropicalis)
        
        xrcc2 [nucleoplasm] (Xenopus tropicalis)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Xenopus tropicalis)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Xenopus tropicalis)
        
        BCDX2 complex [nucleoplasm] (Xenopus tropicalis)
        
        xrcc2 [nucleoplasm] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A0A803K192

Gene Names

xrcc2

Reference Genes

BioGPS Gene:100486989 xrcc2

ENSEMBL:ENSXETG00000045924

KEGG:xtr:100486989 xrcc2

Monarch:100486989 xrcc2

NCBI Gene:100486989 xrcc2

UCSC:A0A803K192 xrcc2

Reference Transcript

RefSeq:XM_002932495.5 xrcc2

Other Identifiers

100486989

GO:0000400

GO:0000724

GO:0003677

GO:0005524

GO:0005657

GO:0005813

GO:0005815

GO:0006281

GO:0006310

GO:0033063

GO:0042148

GO:0140664

Participates

as a component of

BCDX2 complex [nucleoplasm] (Xenopus tropicalis)

Inferred From

XRCC2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_002932541.3

ENSEMBL

ENSXETP00000114089, ENSXETT00000120631, ENSXETG00000045924

Xenbase

XB-GENE-6083458

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