Reactome | ctsz [COPII-coated ER to Golgi transport vesicle]

ctsz [COPII-coated ER to Golgi transport vesicle]

Stable Identifier

R-XTR-5689727

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

COPII-coated ER to Golgi transport vesicle

Synonyms

(Glc)3(GlcNAc)2(Man)9-CTSZ, A0A803JDZ3

Locations in the PathwayBrowser

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Metabolism of proteins (Xenopus tropicalis)

- Post-translational protein modification (Xenopus tropicalis)
  - Asparagine N-linked glycosylation (Xenopus tropicalis)
    - Transport to the Golgi and subsequent modification (Xenopus tropicalis)
      - ER to Golgi Anterograde Transport (Xenopus tropicalis)
        
        COPII-mediated vesicle transport (Xenopus tropicalis)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Xenopus tropicalis)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Xenopus tropicalis)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        ctsz [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        Nucleotide exchange on RAB1 (Xenopus tropicalis)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        ctsz [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        ctsz [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Xenopus tropicalis)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        ctsz [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Xenopus tropicalis)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        ctsz [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)

Vesicle-mediated transport (Xenopus tropicalis)

- Membrane Trafficking (Xenopus tropicalis)
  - ER to Golgi Anterograde Transport (Xenopus tropicalis)
    - COPII-mediated vesicle transport (Xenopus tropicalis)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Xenopus tropicalis)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Xenopus tropicalis)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        ctsz [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
      - Nucleotide exchange on RAB1 (Xenopus tropicalis)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        ctsz [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        ctsz [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
      - RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Xenopus tropicalis)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        ctsz [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Xenopus tropicalis)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)
        
        ctsz [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A0A803JDZ3

Gene Names

ctsz

Reference Genes

ENSEMBL:ENSXETG00000044492

Other Identifiers

100127597

GO:0003824

GO:0006508

GO:0008234

GO:0016787

GO:0140096

Participates

as a member of

glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Xenopus tropicalis)

Other forms of this molecule

ctsz [Golgi lumen]

ctsz [lysosomal lumen]

ctsz [plasma membrane]

ctsz [specific granule lumen]

ctsz [extracellular region]

ctsz [ficolin-1-rich granule lumen]

ctsz [endoplasmic reticulum-Golgi intermediate compartment membrane]

ctsz [endoplasmic reticulum lumen]

Inferred From

(Glc)3(GlcNAc)2(Man)9-CTSZ [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)

Modified Residues

Name

N4-(N-acetylamino)glucosyl-L-asparagine (N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue (ChEBI:59084)) at unknown position

Modification

N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-yl group (ChEBI:59084)

PsiMod Name

N4-(N-acetylamino)glucosyl-L-asparagine

PsiMod Definition

A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.

Cross References

Ensembl

ENSXETP00000106102, ENSXETT00000121727, ENSXETG00000044492

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