Reactome | ccnd1 [cytosol]

ccnd1 [cytosol]

Stable Identifier

R-XTR-68328

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

CCND1, Q6GLD3

Locations in the PathwayBrowser

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Immune System (Xenopus tropicalis)

- Adaptive Immune System (Xenopus tropicalis)
  - Regulation of T cell activation by CD28 family (Xenopus tropicalis)
    - Co-inhibition by PD-1 (Xenopus tropicalis)
      - Regulation of PD-L1(CD274) expression (Xenopus tropicalis)
        
        Regulation of PD-L1(CD274) Post-translational modification (Xenopus tropicalis)
        
        SPOP-mediated proteasomal degradation of PD-L1(CD274) (Xenopus tropicalis)
        
        CDK4:CCND1 phosphorylates SPOP (Xenopus tropicalis)
        
        CDK4:CCND1 [cytosol] (Xenopus tropicalis)
        
        ccnd1 [cytosol] (Xenopus tropicalis)

Signal Transduction (Xenopus tropicalis)

- Signaling by Non-Receptor Tyrosine Kinases (Xenopus tropicalis)
  - Signaling by PTK6 (Xenopus tropicalis)
    - PTK6 Regulates Cell Cycle (Xenopus tropicalis)
      - Activated PTK6 binds CDKN1B (Xenopus tropicalis)
        
        CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Xenopus tropicalis)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Xenopus tropicalis)
        
        CDK4:CCND1 [cytosol] (Xenopus tropicalis)
        
        ccnd1 [cytosol] (Xenopus tropicalis)
        
        p-Y342-PTK6:CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Xenopus tropicalis)
        
        CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Xenopus tropicalis)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Xenopus tropicalis)
        
        CDK4:CCND1 [cytosol] (Xenopus tropicalis)
        
        ccnd1 [cytosol] (Xenopus tropicalis)
      - PTK6 phosphorylates CDKN1B (Xenopus tropicalis)
        
        p-Y342-PTK6:CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Xenopus tropicalis)
        
        CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Xenopus tropicalis)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Xenopus tropicalis)
        
        CDK4:CCND1 [cytosol] (Xenopus tropicalis)
        
        ccnd1 [cytosol] (Xenopus tropicalis)
        
        p-Y88-CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Xenopus tropicalis)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Xenopus tropicalis)
        
        CDK4:CCND1 [cytosol] (Xenopus tropicalis)
        
        ccnd1 [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:Q6GLD3

Gene Names

ccnd1

Reference Genes

BioGPS Gene:448045 ccnd1

ENSEMBL:ENSXETG00000045695

KEGG:xtr:448045 ccnd1

Monarch:448045 ccnd1

NCBI Gene:448045 ccnd1

UCSC:Q6GLD3 ccnd1

Reference Transcript

RefSeq:NM_001005452.1 ccnd1

Other Identifiers

448045

GO:0000082

GO:0000307

GO:0005515

GO:0005634

GO:0005737

GO:0005815

GO:0016538

GO:0051301

GO:1900087

Participates

as an input of

Formation of CDK4/6:CCND complexes (Xenopus tropicalis)

as a component of

Other forms of this molecule

phospho-ccnd1 [cytosol]

phospho-ccnd1 [nucleoplasm]

ccnd1 [nucleoplasm]

Inferred From

Cyclin D [cytosol] (Homo sapiens)

CCND1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001005452.1

ENSEMBL

ENSXETP00000103153, ENSXETT00000110913, ENSXETG00000045695

Xenbase

XB-GENE-6077306

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