Reactome | rpl36a [cytosol]

rpl36a [cytosol]

Stable Identifier

R-XTR-72480

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

RPL36A, Q6DER8

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Xenopus tropicalis)

- Nonsense-Mediated Decay (NMD) (Xenopus tropicalis)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Xenopus tropicalis)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Xenopus tropicalis)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Xenopus tropicalis)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Xenopus tropicalis)
        
        80S ribosome [cytosol] (Xenopus tropicalis)
        
        60S ribosomal complex [cytosol] (Xenopus tropicalis)
        
        rpl36a [cytosol] (Xenopus tropicalis)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Xenopus tropicalis)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Xenopus tropicalis)
        
        80S ribosome [cytosol] (Xenopus tropicalis)
        
        60S ribosomal complex [cytosol] (Xenopus tropicalis)
        
        rpl36a [cytosol] (Xenopus tropicalis)
    - SMG6 hydrolyzes mRNA with premature termination codon (Xenopus tropicalis)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Xenopus tropicalis)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Xenopus tropicalis)
        
        80S ribosome [cytosol] (Xenopus tropicalis)
        
        60S ribosomal complex [cytosol] (Xenopus tropicalis)
        
        rpl36a [cytosol] (Xenopus tropicalis)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Xenopus tropicalis)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Xenopus tropicalis)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Xenopus tropicalis)
        
        80S ribosome [cytosol] (Xenopus tropicalis)
        
        60S ribosomal complex [cytosol] (Xenopus tropicalis)
        
        rpl36a [cytosol] (Xenopus tropicalis)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Xenopus tropicalis)
        
        80S ribosome [cytosol] (Xenopus tropicalis)
        
        60S ribosomal complex [cytosol] (Xenopus tropicalis)
        
        rpl36a [cytosol] (Xenopus tropicalis)
    - p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Xenopus tropicalis)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Xenopus tropicalis)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Xenopus tropicalis)
        
        80S ribosome [cytosol] (Xenopus tropicalis)
        
        60S ribosomal complex [cytosol] (Xenopus tropicalis)
        
        rpl36a [cytosol] (Xenopus tropicalis)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Xenopus tropicalis)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Xenopus tropicalis)
        
        80S ribosome [cytosol] (Xenopus tropicalis)
        
        60S ribosomal complex [cytosol] (Xenopus tropicalis)
        
        rpl36a [cytosol] (Xenopus tropicalis)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Xenopus tropicalis)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Xenopus tropicalis)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Xenopus tropicalis)
        
        80S ribosome [cytosol] (Xenopus tropicalis)
        
        60S ribosomal complex [cytosol] (Xenopus tropicalis)
        
        rpl36a [cytosol] (Xenopus tropicalis)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Xenopus tropicalis)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Xenopus tropicalis)
        
        80S ribosome [cytosol] (Xenopus tropicalis)
        
        60S ribosomal complex [cytosol] (Xenopus tropicalis)
        
        rpl36a [cytosol] (Xenopus tropicalis)
- rRNA processing (Xenopus tropicalis)
  - rRNA processing in the nucleus and cytosol (Xenopus tropicalis)
    - Major pathway of rRNA processing in the nucleolus and cytosol (Xenopus tropicalis)
      - 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Xenopus tropicalis)
        
        60S ribosomal complex [cytosol] (Xenopus tropicalis)
        
        rpl36a [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:Q6DER8

Gene Names

rpl36a

Reference Genes

BioGPS Gene:448673 rpl36a

ENSEMBL:ENSXETG00000018150

KEGG Gene (Xenopus tropicalis):448673 rpl36a

Monarch:448673 rpl36a

NCBI Gene:448673 rpl36a

Reference Transcript

RefSeq:NM_001005095.1 rpl36a

Other Identifiers

448673

GO:0003735

GO:0005198

GO:0005840

GO:0006412

GO:0043226

GO:1990904

Participates

as a component of

Other forms of this molecule

rpl36a [cytosol]

Inferred From

RPL36A,RPL36AL [cytosol] (Homo sapiens)

RPL36A [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001005095.1

Xenbase

XB-GENE-974799

Ensembl

ENSXETP00000039360, ENSXETT00000039360, ENSXETP00000111246, ENSXETT00000123295, ENSXETG00000018150

Cite Us!