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pik3cb [cytosol]
Stable Identifier
R-XTR-74788
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
PIK3CB, Q0IHS8
Locations in the PathwayBrowser
Expand all
Developmental Biology (Xenopus tropicalis)
Nervous system development (Xenopus tropicalis)
Axon guidance (Xenopus tropicalis)
RET signaling (Xenopus tropicalis)
p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K (Xenopus tropicalis)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Xenopus tropicalis)
PI3K alpha, beta, gamma [cytosol] (Xenopus tropicalis)
PI3K beta [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
PI3K alpha, beta, gamma [cytosol] (Xenopus tropicalis)
PI3K beta [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
Hemostasis (Xenopus tropicalis)
Cell surface interactions at the vascular wall (Xenopus tropicalis)
Tie2 Signaling (Xenopus tropicalis)
Interaction of Tie2 and p85 of PI3K (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
p85 bound to Tie2 [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
Platelet activation, signaling and aggregation (Xenopus tropicalis)
GPVI-mediated activation cascade (Xenopus tropicalis)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Xenopus tropicalis)
PI3K alpha, beta, gamma [cytosol] (Xenopus tropicalis)
PI3K beta [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
Immune System (Xenopus tropicalis)
Cytokine Signaling in Immune system (Xenopus tropicalis)
Signaling by Interleukins (Xenopus tropicalis)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Xenopus tropicalis)
Regulation of signaling by CBL (Xenopus tropicalis)
CBL ubiquitinates PI3K (Xenopus tropicalis)
FYN-like kinases:p(Y731)-CBL:GRB2:Ubiquitinated p85-containing Class 1A PI3Ks [cytosol] (Xenopus tropicalis)
K63polyUb-p85-containing Class 1A PI3Ks [cytosol] (Xenopus tropicalis)
K63polyUb-PI3K beta [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
FYN-like kinases:p(Y731)-CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] (Xenopus tropicalis)
PI3K alpha, beta, gamma [cytosol] (Xenopus tropicalis)
PI3K beta [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
Innate Immune System (Xenopus tropicalis)
Fc epsilon receptor (FCERI) signaling (Xenopus tropicalis)
Role of LAT2/NTAL/LAB on calcium mobilization (Xenopus tropicalis)
PI3K associates with phosphorylated GAB2 (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
Phosphorylation of PIP2 to PIP3 by PI3K (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
Metabolism (Xenopus tropicalis)
Metabolism of lipids (Xenopus tropicalis)
Phospholipid metabolism (Xenopus tropicalis)
PI Metabolism (Xenopus tropicalis)
Synthesis of PIPs at the plasma membrane (Xenopus tropicalis)
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Xenopus tropicalis)
PIK3C(1) [cytosol] (Xenopus tropicalis)
PIK3CB:PIK3R1 [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
PIK3CB:PIK3R2 [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
PIK3CB:PIK3R3 [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Xenopus tropicalis)
PIK3(2) [cytosol] (Xenopus tropicalis)
PIK3CB:PIK3R1 [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
PIK3CB:PIK3R2 [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
PIK3CB:PIK3R3 [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
Intracellular signaling by second messengers (Xenopus tropicalis)
PIP3 activates AKT signaling (Xenopus tropicalis)
Negative regulation of the PI3K/AKT network (Xenopus tropicalis)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Xenopus tropicalis)
PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
Activator:PI3K [plasma membrane] (Xenopus tropicalis)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
Activator:PI3K [plasma membrane] (Xenopus tropicalis)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
MAPK family signaling cascades (Xenopus tropicalis)
MAPK1/MAPK3 signaling (Xenopus tropicalis)
RAF/MAP kinase cascade (Xenopus tropicalis)
RAS:GTP binds PI3K (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
p21 RAS:GTP:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
Signaling by Erythropoietin (Xenopus tropicalis)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) (Xenopus tropicalis)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-GAB1 binds PI3K (Xenopus tropicalis)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-GAB1:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K alpha, gamma [cytosol] (Xenopus tropicalis)
PIK3CB:PIK3R1 [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
PI3K alpha, gamma [cytosol] (Xenopus tropicalis)
PIK3CB:PIK3R1 [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
EPO:phospho-EPOR:phospho-JAK2:LYN:phospho-IRS2 binds PI3K (Xenopus tropicalis)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-Y-IRS2:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K alpha, gamma [cytosol] (Xenopus tropicalis)
PIK3CB:PIK3R1 [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
PI3K alpha, gamma [cytosol] (Xenopus tropicalis)
PIK3CB:PIK3R1 [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
PI3K alpha, gamma [cytosol] (Xenopus tropicalis)
PIK3CB:PIK3R1 [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
PI3K bound to EPOR [plasma membrane] (Xenopus tropicalis)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K alpha, gamma [cytosol] (Xenopus tropicalis)
PIK3CB:PIK3R1 [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-GAB1:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K alpha, gamma [cytosol] (Xenopus tropicalis)
PIK3CB:PIK3R1 [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-Y-IRS2:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K alpha, gamma [cytosol] (Xenopus tropicalis)
PIK3CB:PIK3R1 [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by ALK (Xenopus tropicalis)
PI3K synthesizes PIP3 downstream of ALK (Xenopus tropicalis)
Active ALK:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
Signaling by Insulin receptor (Xenopus tropicalis)
Insulin receptor signalling cascade (Xenopus tropicalis)
IRS-mediated signalling (Xenopus tropicalis)
PI3K Cascade (Xenopus tropicalis)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Xenopus tropicalis)
PI3K-containing complexes [cytosol] (Xenopus tropicalis)
Activated FGFR bound to PI3K [cytosol] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 bind PI3K (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
Signaling by LTK (Xenopus tropicalis)
Active LTK receptor binds PI3K (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
p-5Y LTK dimer:ALKAL1,2:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
Signaling by NTRKs (Xenopus tropicalis)
Signaling by NTRK1 (TRKA) (Xenopus tropicalis)
PI3K/AKT activation (Xenopus tropicalis)
Active IRS recruits PI3K to the plasma membrane and activates it (Xenopus tropicalis)
Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
PI3K produces PIP3 and other phosphatidyl inositides (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
Signaling by PDGF (Xenopus tropicalis)
Downstream signal transduction (Xenopus tropicalis)
PI3-kinase binds to the active receptor (Xenopus tropicalis)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Xenopus tropicalis)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
Signaling by SCF-KIT (Xenopus tropicalis)
Synthesis of PIP3 from PIP2 by PI3K (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Xenopus tropicalis)
IGF1R signaling cascade (Xenopus tropicalis)
IRS-related events triggered by IGF1R (Xenopus tropicalis)
IRS-mediated signalling (Xenopus tropicalis)
PI3K Cascade (Xenopus tropicalis)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Xenopus tropicalis)
PI3K-containing complexes [cytosol] (Xenopus tropicalis)
Activated FGFR bound to PI3K [cytosol] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 bind PI3K (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
Signaling by VEGF (Xenopus tropicalis)
VEGFA-VEGFR2 Pathway (Xenopus tropicalis)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
pik3cb [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:Q0IHS8
Gene Names
pik3cb
Reference Genes
BioGPS Gene:780390 pik3cb
ENSEMBL:ENSXETG00000008254
KEGG Gene (Xenopus tropicalis):780390 pik3cb
Monarch:780390 pik3cb
NCBI Gene:780390 pik3cb
Reference Transcript
RefSeq:NM_001079460.1 pik3cb
Participates
as a component of
K63polyUb-PI3K beta [cytosol] (Xenopus tropicalis)
PI3K beta [cytosol] (Xenopus tropicalis)
PIK3CB:PIK3R2 [cytosol] (Xenopus tropicalis)
PIK3CB:PIK3R1 [cytosol] (Xenopus tropicalis)
PIK3CB:PIK3R3 [cytosol] (Xenopus tropicalis)
as a member of
PI3K-catalytic subunit [cytosol] (Xenopus tropicalis)
Inferred From
PIK3CB [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001072928.1
Xenbase
XB-GENE-482674
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