Reactome | xrcc4 [nucleoplasm]

xrcc4 [nucleoplasm]

Stable Identifier

R-XTR-75911

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

nucleoplasm

Synonyms

XRCC4, A8WH10

Locations in the PathwayBrowser

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DNA Repair (Xenopus tropicalis)

- DNA Double-Strand Break Repair (Xenopus tropicalis)
  - Nonhomologous End-Joining (NHEJ) (Xenopus tropicalis)
    - POLL or POLM extends aligned DNA DSB ends to fill gaps (Xenopus tropicalis)
      - p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6:p-S516,S645-DCLRE1C:XRCC4:LIG4:NHEJ1:POLL,POLM:Extended ligatable DNA DSB ends [nucleoplasm] (Xenopus tropicalis)
        
        XRCC4:LIG4 [nucleoplasm] (Xenopus tropicalis)
        
        XRCC4 homodimer [nucleoplasm] (Xenopus tropicalis)
        
        xrcc4 [nucleoplasm] (Xenopus tropicalis)
      - p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6:p-S516,S645-DCLRE1C:XRCC4:LIG4:NHEJ1:POLL,POLM:Ligatable DNA DSB ends [nucleoplasm] (Xenopus tropicalis)
        
        XRCC4:LIG4 [nucleoplasm] (Xenopus tropicalis)
        
        XRCC4 homodimer [nucleoplasm] (Xenopus tropicalis)
        
        xrcc4 [nucleoplasm] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A8WH10

Gene Names

xrcc4

Reference Genes

BioGPS Gene:100127743 xrcc4

ENSEMBL:ENSXETG00000027814

KEGG Gene (Xenopus tropicalis):100127743 xrcc4

Monarch:100127743 xrcc4

NCBI Gene:100127743 xrcc4

Reference Transcript

RefSeq:NM_001113080.2 xrcc4

Other Identifiers

100127743

GO:0003677

GO:0005634

GO:0006281

GO:0006302

GO:0006303

GO:0006310

GO:0006974

GO:0043226

Participates

as a component of

XRCC4 homodimer [nucleoplasm] (Xenopus tropicalis)

Other forms of this molecule

xrcc4 [nucleoplasm]

Inferred From

XRCC4 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001106551.1

Xenbase

XB-GENE-943956

Ensembl

ENSXETG00000027814, ENSXETT00000057859, ENSXETP00000057859

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