Reactome | LOC116407943 [extracellular region]

LOC116407943 [extracellular region]

Stable Identifier

R-XTR-877346-2

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

extracellular region

Synonyms

IFNA6, A0A219UQI0

Locations in the PathwayBrowser

Expand all

Immune System (Xenopus tropicalis)

- Cytokine Signaling in Immune system (Xenopus tropicalis)
  - Interferon Signaling (Xenopus tropicalis)
    - Interferon alpha/beta signaling (Xenopus tropicalis)
      - Activation of JAK kinases (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
        
        p-TYK2:p-IFNAR1:SOCS-1/SOCS-3:IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
      - Formation of p-STAT1 homodimer (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
      - IFN alpha/beta binds to IFNAR2 (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
      - Phosphorylation of INFAR1 by TYK2 (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
      - Phosphorylation of STAT2 (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
      - Recruitment of IFNAR1 (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
      - Recruitment of STAT2 to p-IFNAR1 (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
      - Regulation of IFNA/IFNB signaling (Xenopus tropicalis)
        
        Dephosphorylation of JAK1 by SHP1 (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
        
        Dephosphorylation of STAT1 by SHP2 (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:STAT1 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
        
        Dephosphorylation of TYK2 by PTP1B (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
      - Release of p-STAT2:p-STAT1 dimer (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Xenopus tropicalis)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Xenopus tropicalis)
        
        IFNA [extracellular region] (Xenopus tropicalis)
        
        Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)
        
        LOC116407943 [extracellular region] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A0A219UQI0

Gene Names

LOC116407943

Reference Genes

ENSEMBL:ENSXETG00000029972

KEGG Gene (Xenopus tropicalis):116407943 LOC116407943

Reference Transcript

RefSeq:XM_031894282.1 LOC116407943

Other Identifiers

116407943

GO:0005125

GO:0005126

GO:0005132

GO:0005576

GO:0006952

GO:0007165

GO:0023052

GO:0050896

GO:0051607

GO:0098542

GO:0098772

Participates

as a member of

Homologues of IFNA6 [extracellular region] (Xenopus tropicalis)

Other forms of this molecule

LOC116407943 [extracellular region]

Inferred From

IFNA6 [extracellular region] (Homo sapiens)

Cross References

RefSeq

XP_031750142.1

Ensembl

ENSXETT00000060588, ENSXETP00000063859, ENSXETG00000029972

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